[HTML][HTML] Immunogenicity of TNF-inhibitors

S Atiqi, F Hooijberg, FC Loeff, T Rispens… - Frontiers in …, 2020 - frontiersin.org
… drew attention toward the immunogenicity of TNFi showed a … immunogenicity adequate
drug level measurements are essential. In this review these different aspects of immunogenicity

[HTML][HTML] What is the clinical relevance of TNF inhibitor immunogenicity in the management of patients with rheumatoid arthritis?

P Mehta, JJ Manson - Frontiers in Immunology, 2020 - frontiersin.org
… making interpretation of immunogenicity data from published … monitoring (TDM) and
immunogenicity testing have not been … relevance of TDM and immunogenicity testing of TNFis in …

Personalized medicine in rheumatoid arthritis: How immunogenicity impacts use of TNF inhibitors

C Bodio, C Grossi, F Pregnolato, EG Favalli… - Autoimmunity …, 2020 - Elsevier
… Our study confirms that ETA displays the lowest immunogenicity in comparison to IFX and
… clinical response, further supporting that immunogenicity plays a role in secondary failure to …

Pharmacological strategies for mitigating anti-TNF biologic immunogenicity in rheumatoid arthritis patients

CA Fernandez - Current opinion in pharmacology, 2023 - Elsevier
immunogenicity. In this review, we highlight the limitations of MTX for mitigating TNFα inhibitor
immunogenicity, … for decreasing the risk of immunogenicity during TNFα inhibitor therapy …

Secondary failure of TNF‐α inhibitors in clinical practice

A Owczarczyk‐Saczonek, W Owczarek… - Dermatologic …, 2019 - Wiley Online Library
Immunogenicity is defined as the ability of a particular substance to induce a humoral or
cell-… for both clinical practice and patients in which TNF inhibitors fail. ELISA is used in clinical …

Immunogenicity of biologic agents in rheumatology

V Strand, J Goncalves, JD Isaacs - Nature Reviews Rheumatology, 2021 - nature.com
… Furthermore, infliximab (the only chimeric monoclonal antibody among the five available
TNF inhibitors) is more immunogenic than any of the other four TNF inhibitors 4 (Table 1). …

Methotrexate and TNF inhibitors affect long-term immunogenicity to COVID-19 vaccination in patients with immune-mediated inflammatory disease

RH Haberman, S Um, JE Axelrad, RB Blank… - The Lancet …, 2022 - thelancet.com
… , TNF inhibitors (especially in combination with methotrexate) led to further decreased rates
of immunogenicity … Most initial studies did not demonstrate any effect of TNF inhibitors on …

[HTML][HTML] Immunogenicity of subcutaneous TNF inhibitors and its clinical significance in real-life setting in patients with spondyloarthritis

J Hiltunen, P Parmanne, T Sokka, T Lamberg… - Rheumatology …, 2022 - Springer
… and ADAb in SpA patients using TNF inhibitors with the exception of etanercept is useful both
… showed that therapeutic drug monitoring of TNF inhibitors leads to better clinical response …

Immunogenicity of BNT162b2 mRNA SARS-CoV-2 vaccine in patients with psoriatic arthritis on TNF inhibitors

V Venerito, P Stefanizzi, M Fornaro, F Cacciapaglia… - RMD open, 2022 - rmdopen.bmj.com
… This study analyses the immunogenicity of the BNT162b2 vaccine in patients with PsA on
TNFi, … Like recent reports,9 the immunogenicity of BNT162b2 was not hindered in patients with …

Immunogenicity of the COVID-19 mRNA vaccine in adolescents with juvenile idiopathic arthritis on treatment with TNF inhibitors

D Dimopoulou, G Vartzelis, F Dasoula… - Annals of the …, 2022 - ard.bmj.com
… was to evaluate the immunogenicity of the BNT162b2 COVID… Blood samples for the evaluation
of vaccine immunogenicity … on comparison of the immunogenicity between the different …