… primary immunodeficiency and defined by profoundly impaired … Altered function of Toll-like
receptors, which recognize … DR, proteins involved in activation of T cells, increased on CD14 …

… Upon secondary encounter of the specific antigen or activation via Toll-like receptor (TLR) …
We examined the composition of circulating B cells and T cells in patients with CVID. As …

… For both CD8 + and CD4 + T cell subsets, we also classified … IgA + ) plasma cells, present
with a disturbed T cell homeostasis and … of Toll-like, RIG-I-like, and NOD-like receptor signaling …

… Common variable immunodeficiency (CVID) due to ICOS … small number of patients whose T
cells lacked ICOS expression … such as impaired anti-viral and anti-tumor immune responses (…

… Toll-like receptors (TLRs) are pattern recognition receptors that mediate … impairments
from a patient with severe T cell immunodeficiency [9] to another with normal CD4 + T cells and …

… present with variable degrees of immunodeficiency. Accordingly, … kinase; TCR, T cell receptor;
TLR, toll-like receptor; TNFR1, … a combined immunodeficiency with impaired T and B cell …

… cause of death in the human immunodeficiency virus (HIV)-… [62]; the impairment of CD4+
and CD8+ T cell responses to Mtb … + T cells before the depletion of generalized CD4+ T cells in …

… In the T cell compartment, reduced peripheral T cells have … , for instance, in reducing
toll-like receptor (TLR)-induced … impaired HDL levels/function and immune activation in CVID. …

… immunity for a T cell-dependent immune response, as they are significantly impaired in the
… to short-lived plasma cells, having accumulated variable region mutations due to positive …

… disease [MSMD], Toll-like receptor [TLR] defects, and … cells and CD40 ligand on activated T
cells is essential for B-… TLR3, and impaired activation of a downstream antiviral response, can …