[图书][B] Sex Differences in Hypertension and the Role of Endothelial TRPV4 Channels in Cerebrovascular and Cognitive Function

LC Chambers - 2022 - search.proquest.com
impairment in the small arteries and arterioles in the brain. … property of arteries and arterioles
to constrict in response to … decreases endothelium-dependent dilation in cerebral arteries in …

Endothelial KIR2 channel dysfunction in aged cerebral parenchymal arterioles

FD Polk, MA Hakim, JF Silva… - American Journal of …, 2023 - journals.physiology.org
… with lower vasodilatory response to purinergic receptor 47 … smooth muscle cells (endothelium-dependent
hyperpolarization), … structure of parenchymal arterioles by hypertension and the …

Hypertension, neurodegeneration, and cognitive decline

A Pacholko, C Iadecola - Hypertension, 2024 - Am Heart Assoc
… in both extracranial and intracranial cerebral arteries, 16,33 increasing … dysfunction, 66 and
endothelium-dependent vasodilatory responses to acetylcholine are diminished in arteriolar

Angiotensin II Directly Increases Endothelial Calcium and Nitric Oxide in Kidney and Brain Microvessels In Vivo With Reduced Efficacy in Hypertension

A Becerra Calderon, UN Shroff, S Deepak… - Journal of the …, 2024 - Am Heart Assoc
dysfunction and altered hemodynamic responses in … that trigger or regulate
endotheliumdependent vasodilation, … in the intact brain and kidney resistance arterioles is an …

CD4+ Regulatory T Lymphocytes Prevent Impaired Cerebral Blood Flow in Angiotensin II‐Induced Hypertension

MF Iulita, S Duchemin, D Vallerand… - Journal of the …, 2019 - Am Heart Assoc
dysfunction of mesenteric arteries. Whether Treg modulate the cerebrovascular damage
induced by hypertension is … Endotheliumdependent CBF responses were measured after the …

Inflammation: a mediator between hypertension and neurodegenerative diseases

J Youwakim, H Girouard - American Journal of Hypertension, 2021 - academic.oup.com
… is the most prevalent and modifiable risk factor for stroke, vascular cognitive impairment, …
Increased ROS production Cerebral arteries (basilar artery, middle cerebral arteries and the …

Challenges in the evaluation of endothelial cell dysfunction: a statement from the European Society of Hypertension Working Group on Endothelin and Endothelial …

GP Rossi, M Barton, N Dhaun, D Rizzoni… - … of Hypertension, 2023 - journals.lww.com
… of evaluating functional vascular responses to stimulation or … evoked by ET-1 than other
conduit arteries [39] . It is also … indicating activation of endothelium-dependent contractions as …

Female mice are protected from impaired parenchymal arteriolar TRPV4 function and impaired cognition in hypertension

LC Chambers, M Yen, WF Jackson… - American Journal of …, 2023 - journals.physiology.org
… Our laboratory has shown that endothelium-dependent dilation in cerebral parenchymal
arterioles … Our goal was to determine sex differences in response to hypertension in young mice. …

Low-dose angiotensin II supplementation restores flow-induced dilation mechanisms in cerebral arteries of Sprague-Dawley rats on a high salt diet

A Matic, I Jukic, Z Mihaljevic, N Kolobaric… - … of hypertension, 2022 - journals.lww.com
… the hypothesis that impaired endothelium-dependent vascular responses are affected by …
fibroblasts and intact arteries [18] , leading to endothelial dysfunction and hypertension [19] . …

The contribution of gut microbiota and endothelial dysfunction in the development of arterial hypertension in animal models and in humans

J Maiuolo, C Carresi, M Gliozzi, R Mollace… - International Journal of …, 2022 - mdpi.com
… that hypertension reduces endothelium-dependent relaxation in both large and small arteries
[… isolated from pigs’ hearts showed a dose dependent vasodilatory response mediated by …