Tumor-associated macrophages in nanomaterial-based anti-tumor therapy: as target spots or delivery platforms
… drug delivery platforms is also highlighted, offering improved … TAMs have been identified
as a key inducer of angiogenesis, … research of targeted delivery of small molecule inhibitors of …
as a key inducer of angiogenesis, … research of targeted delivery of small molecule inhibitors of …
Macrophages as promising carriers for nanoparticle delivery in anticancer therapy
A Wróblewska, A Szczygieł… - International Journal …, 2023 - Taylor & Francis
… depleted TAMs, reduced angiogenesis, and prevented the … for the delivery of anticancer
drugs due to their better … receptors and adhesion molecules using genetic engineering, as well …
drugs due to their better … receptors and adhesion molecules using genetic engineering, as well …
CD276 is an important player in macrophage recruitment into the tumor and an upstream regulator for PAI-1
S Durlanik, K Fundel-Clemens, C Viollet, HJ Huber… - Scientific Reports, 2021 - nature.com
… Based on quantification analysis done by flow cytometry, we detected increased … angiogenesis,
tumor cell invasion and motility, TAM can suppress the anti-tumor T cell responses 45 . In …
tumor cell invasion and motility, TAM can suppress the anti-tumor T cell responses 45 . In …
[图书][B] Magnetically Actuated Alginate Scaffolds: Effects on Macrophage Function and Regenerative Outcomes
L Steele - 2020 - search.proquest.com
… angiogenesis requires sustained, localized delivery of … , it significantly increased the expression
of several angiogenic factors … By day 10 pi, the macrophage-recruiting hydrogels display …
of several angiogenic factors … By day 10 pi, the macrophage-recruiting hydrogels display …
[HTML][HTML] HIF1α epigenetically repressed macrophages via CRISPR/Cas9-EZH2 system for enhanced cancer immunotherapy
Y Dong, S Zhang, X Gao, D Yin, T Wang, Z Li, Z Wan… - Bioactive Materials, 2021 - Elsevier
… angiogenesis. Together, our study has not only identified a promising cellular and molecular
… macrophages would hijack existent macrophage recruiting signals and activate immune …
… macrophages would hijack existent macrophage recruiting signals and activate immune …
Angiogenesis in lymph nodes is a critical regulator of immune response and lymphoma growth
L Menzel, UE Höpken, A Rehm - Frontiers in immunology, 2020 - frontiersin.org
… that supports angiogenesis and increased LN vascularization (1… RA is presumably provided
by neurons localized adjacent to … molecules and is not a reliable indicator of angiogenesis in …
by neurons localized adjacent to … molecules and is not a reliable indicator of angiogenesis in …
Macrophage polarization states in the tumor microenvironment
AJ Boutilier, SF Elsawa - International journal of molecular sciences, 2021 - mdpi.com
… increased in inflammatory and angiogenic settings. Ang2 expression in cultured endothelial
cells is increased … therapy response in murine models of several different tumor types [139]. …
cells is increased … therapy response in murine models of several different tumor types [139]. …
Targeting macrophages: friends or foes in disease?
… responses, causing tissue damage or helping in tissue repair. Knowledge in macrophage
polarization has significantly increased in the … Therefore, dissection of the molecular basis of …
polarization has significantly increased in the … Therefore, dissection of the molecular basis of …
Tumor-associated macrophages in cancer: recent advancements in cancer nanoimmunotherapies
N Kumari, SH Choi - Journal of Experimental & Clinical Cancer Research, 2022 - Springer
… and angiogenesis while suppressing the immune response and … local delivery of
nanotherapeutics to nearby tumor cells and … MMPs, all of which increase angiogenesis through …
nanotherapeutics to nearby tumor cells and … MMPs, all of which increase angiogenesis through …
Macrophages as a potential immunotherapeutic target in solid cancers
… Nevertheless, several small molecule and antibody-based … -1 resulted in an enhanced
tumor response compared to anti-… delivery of IFNγ inhibited tumor growth and angiogenesis by …
tumor response compared to anti-… delivery of IFNγ inhibited tumor growth and angiogenesis by …