… represents only a part of the total DNA damage [60,61]. In the … affects clastogenic by inducing
cytogenetic changes. These … of chromosomal aberrations by hydroquinone in V79 cells. …

… Primary DNA damage in PBLs treated with STH before and after irradiation was assessed …
demonstrated by slightly higher cytotoxicity, higher level of primary DNA damage, and slightly …

… However, exposure to single arbutin affected the levels of primary DNA damage in renal
cells which could be related to metabolic conversion of arbutin into hydroquinone, whose …

… As demonstrated, CL and SL did not cause DNA damage and fragmentation, chromatin …
et al., in 2019, assessed the cytotoxic effects of tert-butyl hydroquinone (TBHQ) on HUVECs. …

… significant biological effects, including elevated DNA damage (… Evaluation of cytotoxicity
followed the recommendations of … NBUD, another marker of cytogenetic damage, was higher in …

… DNA damaging effect was due to the formation of hydroxyl radicals generated in the
quinone/hydroquinone … The same cell culture was used for testing genotoxic and cytotoxic effects …

… vivo genotoxicity while providing mechanistic insight into the type of DNA damage and if
DNA damage … ≤75% cytotoxicity were acceptable for ToxTracker analysis. A compound was …

… ACN (>99%) containing hydroquinone monoethyl ether as polymerization inhibitor was … of
DNA damage and the percentage of cells with LMW DNA as an indicator of cytotoxicity in the …

… Recent evidence indicates that an underlying cytogenetic abnormality (aneuploidy,
asymmetrical chromosome aberrations, presence of micronuclei) in an early precursor cell …

… above an effect threshold, then permanent DNA damage can occur… Metabolite production,
particularly hydroquinone (the … (ie, non-clonal cytogenetic abnormalities identified in surrogate …