… utility of circulating tumor cells (CTCs) in the diagnosis and management of cancer has drawn
… The CTCs were then cultured in vitro for further downstream applications, thus confirming …

… of cancer in the patient.We now know tumor cells can shed from the tumor and enter the
circulation … These cells are called circulating tumor cells (CTCs). CTCs can also enter the bone …

… by malignant cells that dissociate from the primary tumor and … These cells are referred to as
“circulating tumor cells” (CTCs) and … cancer (CRPC) and derived a permanent ex vivo culture …

… In addition, the growing number of highly sophisticated CTC enrichment and isolation …
In biliary tract cancer, a single-cell assay for detecting CTCs allowed identification of both …

… Of note, the time-dependent variation of CTC concentration observed in our case was
clearly due to infusion of trans-species cultured cells, and does not resemble the anticipated …

… targeting paves a new way to isolate a wide spectrum of CTC subpopulations for more
accurate and sensitive cancer prognosis and feasible in vitro culture. This review places …

… human white blood cells (WBCs) and cultured cancer cells revealed that there … cell lung
cancer cell lines) of cancer cells were smaller than 10 μm. As a result, it was challenging for cell …

… Nevertheless, after advanced therapy, some patients on these regimens can eventually
relapse because cancer cells may find additional pathways to continue growing and spreading (…

… , microfluidic devices and cell culture model expansion for culturing CTCs heterogeneity will
… preclinical studies use cells grown on 2D culture that are mostly flat, whereas a 3D culture …

… cell–cell interactions.163, 164 As the 2D culture does not truly mimic 3D TME, cellular signaling
and drug sensitivity of cancer cells cultured … and fate of cells cultured on 2D monolayer …