Objective The research aims for finding the possibility of buccal delivery of celecoxib from an
in situ mucoadhesive nanogel, and in vitro evaluation of the gel to evidence the enhanced
permeation of drug from buccal mucosa. Materials and methods Six formulations of
celecoxib loaded NLCs were prepared using stearic acid and oleic acid in different ratio in
aqueous solution of poloxamer by emulsion solvent evaporation technique. The
physicochemical evaluations of the celecoxib loaded NLC (CeL-NLC) were carried out. The …