In vitro growth inhibitory effect of selected 18β-glycyrrhetinic acid esters on Theileria annulata
K Buvanesvaragurunathan, J Ganesh, SN Kumar… - Experimental …, 2022 - Elsevier
Glycyrrhetinic acid (GA) is one of the important Pentacyclic Triterpenoids (PT) found in the
roots of licorice. This study aimed to evaluate the in vitro growth inhibitory effect of 18β-GA
(18β-Glycyrrhetinic acid) and C-30 esters against Theileria annulata, the causative agent of
Tropical Bovine Theileriosis. C-30 esters of 18β-GA were synthesized and their structures
were elucidated using spectroscopy. The pharmacodynamic properties of 18β-GA and its C-
30 esters were predicted using DataWarrior and Swiss ADME tools. Cattle isolates of T …
roots of licorice. This study aimed to evaluate the in vitro growth inhibitory effect of 18β-GA
(18β-Glycyrrhetinic acid) and C-30 esters against Theileria annulata, the causative agent of
Tropical Bovine Theileriosis. C-30 esters of 18β-GA were synthesized and their structures
were elucidated using spectroscopy. The pharmacodynamic properties of 18β-GA and its C-
30 esters were predicted using DataWarrior and Swiss ADME tools. Cattle isolates of T …
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