… of non-viral vectors is the protection of carried gene therapy … of viral and non-viral vectors
in gene therapy drug delivery are … mimicking nanofiber scaffolds with their controlled delivery …

… scaffold system for non-viral CRISPR/Cas9 genome editing. We hypothesize that scaffold-mediated
delivery … that would be effective for genome editing in tissue engineering applications…

… formation by combining gene delivery with functional scaffolds to create gene-activated …
long-term gene delivery properties remains a challenge. In this study, a non-viral DNA delivery …

… Electrospun nanofibrous scaffolds area is the leading research field in gene therapy with
their … In this chapter, detailed information about gene therapy, comparison of viral with non-viral …

… for the non-viral vectors to … non-viral gene delivery because of their facile synthesis and
flexible characteristics [ Citation 51 ] . The polymers are capable of being intimate with the genetic …

… developed a CRISPRa non-viral gene delivery platform by immobilizing non-viral CRISPRa
complexes into a biocompatible hydrogel/nanofiber (Gel/NF) composite scaffold. The Gel/NF …

… Natural polymers have received much attention in many medical fields as wound dressings,
adsorbents, drug delivery, and medical scaffolds due to properties such as metabolic …

… Beyond non-viral delivery of nucleic acids, CRISPR/Cas9 components were also delivered
in a localized and non-viral manner via electrospun scaffolds. Specifically, using mussel-…

… non-viral gene therapy could become highly relevant in the near future and is the focus of this
review. Here we evaluate promising in vitro and in vivo non-viral … these non-viral strategies …

… Naked plasmids and non-viral vectors initiate milder … The plasmid can transfect cells in
vivo but has low in vitro efficiency. … The use of nanofiber scaffolds to develop 3D nanofiber …