Challenges of gene delivery to the central nervous system and the growing use of biomaterial vectors
… The cellular uptake of viral gene delivery vectors is referred to as transduction, while uptake
of non-viral gene delivery vectors is referred to as transfection. Vector systems protect the …
of non-viral gene delivery vectors is referred to as transfection. Vector systems protect the …
Electrospun fiber-mediated delivery of neurotrophin-3 mRNA for neural tissue engineering applications
… Alternatively, viral or non-viral DNA or RNA delivery can … and polymer-based gene delivery
vehicles and incorporation of … (Ψ) improve the delivery efficiency of bioactive mRNA and …
vehicles and incorporation of … (Ψ) improve the delivery efficiency of bioactive mRNA and …
Genetically engineered electrospinning contributes to spinal cord injury repair by regulating the immune microenvironment
Y Sun, J Wu, L Zhou, W Wang, H Wang… - … in Bioengineering and …, 2024 - frontiersin.org
… gene delivery, providing a new strategy for the construction of electrospun scaffolds for nerve
repair in gene therapy. … gene transfection and biological factor nanofiber delivery system …
repair in gene therapy. … gene transfection and biological factor nanofiber delivery system …
Injectable, hyaluronic acid-based scaffolds with macroporous architecture for gene delivery
A Ehsanipour, T Nguyen, T Aboufadel… - Cellular and Molecular …, 2019 - Springer
… Controlled delivery of gene therapy vectors from scaffolds requires cell-… scaffolds containing
cell-scale macropores. However, relative efficacy of in vivo gene delivery from scaffolds …
cell-scale macropores. However, relative efficacy of in vivo gene delivery from scaffolds …
Plasmid containing VEGF-165 and ANG-1 dual genes packaged with fibroin-modified PEI to promote the regeneration of vascular network and dermal tissue
P Pan, J Li, X Liu, C Hu, M Wang, W Zhang, M Li… - Colloids and Surfaces B …, 2023 - Elsevier
… in the scaffold and accelerated the regeneration of dermal tissue. The gene delivery system
… not only in the regeneration of vascular-containing tissues, but also in tumor gene therapy. …
… not only in the regeneration of vascular-containing tissues, but also in tumor gene therapy. …
Electrospun gelatin matrices with bioactive pDNA polyplexes
P Pankongadisak, E Tsekoura, O Suwantong… - International journal of …, 2020 - Elsevier
… electrospun nanofiber mats as gene delivery … non-viral gene carriers, polyethylenimine
(PEI) and its derivatives have been widely used to deliver expression systems for gene therapy […
(PEI) and its derivatives have been widely used to deliver expression systems for gene therapy […
Multifunctional scaffolds and synergistic strategies in tissue engineering and regenerative medicine
… The nanofiber scaffolds were effective in suppressing tissue acute inflammation (decreased …
nHA was employed as a non-viral gene transfer. Alginate hydrogels were loaded with …
nHA was employed as a non-viral gene transfer. Alginate hydrogels were loaded with …
Localized delivery of CRISPR/dCas9 via layer-by-layer self-assembling peptide coating on nanofibers for neural tissue engineering
… to develop an effective non-viral approach to deliver CRISPR/… were seeded on aligned
nanofiber scaffolds at 30,000 cells cm −2 … -mediated gene delivery platforms locally released the …
nanofiber scaffolds at 30,000 cells cm −2 … -mediated gene delivery platforms locally released the …
Co-delivery of luteolin and TGF-β1 plasmids with ROS-responsive virus-inspired nanoparticles for microenvironment regulation and chemo-gene therapy of …
Y Ding, H Wang, Y Wang, L Li, J Ding, C Yuan, T Xu… - Nano Research, 2022 - Springer
… The gene delivery vector plays a critical role in gene therapy … positive results in IDD gene
therapy, their safety problems/side … method of non-viral mediated gene therapy with high safety …
therapy, their safety problems/side … method of non-viral mediated gene therapy with high safety …
Electrospinning nanofibers for therapeutics delivery
… absorption of drug delivery systems into the body [45]. Electrospun nanofiber scaffolds offer
a … The cumulative releases of plasmid DNA and the non-viral gene delivery vector from the …
a … The cumulative releases of plasmid DNA and the non-viral gene delivery vector from the …