Gene therapy in wound healing using nanotechnology

C Pang, KS Fan, L Wei, MK Kolar - Wound Repair and …, 2021 - Wiley Online Library
… systems for siRNA are categorized into viral and non-viral vectors (eg, peptides, polymers, …
Electrospun nanofiber scaffold (PLA/PLC) + plasmid DNA KGF Mice full thickness wounds …

The osteogenic and angiogenic potential of microRNA-26a deliveredviaa non-viral delivery peptide for bone repair

P Chambers, M Ziminska, A Elkashif… - … Clinics and Research, 2023 - journals.lww.com
… ) gene therapy has emerged as a promising area of research, with miRNAs capable of regulating
multiple gene … peptide RALA can efficiently deliver miR-26a to MSCs in vitro to regulate …

Nanocarriers, progenitor cells, combinational approaches, and new insights on the retinal therapy

E Pishavar, H Luo, J Bolander, A Atala… - International Journal of …, 2021 - mdpi.com
… available drug delivery systems and combination therapies together with challenges associated
with each approach. As the last step, we discuss the application of nanofibrous scaffolds

Gene immobilization on alginate/polycaprolactone fibers through electrophoretic deposition to promote in situ transfection efficiency and biocompatibility

WW Hu, JC Ting - International journal of biological macromolecules, 2019 - Elsevier
… Therefore, substrate-mediated gene delivery is developed to … a feasible technique to fabricate
nanofibrous scaffolds. It not only … the adjustability of non-viral vector delivery to fulfill clinical …

Gene therapy to enhance angiogenesis in chronic wounds

E Shaabani, M Sharifiaghdam, R Faridi-Majidi… - Molecular Therapy …, 2022 - cell.com
… of gene therapy, efficient delivery of … delivery methods is crucial for a favorable prognosis
of the healing process. This article presents an overview of gene therapy and non-viral delivery

Hydrophilic surface functionalization of electrospun nanofibrous scaffolds in tissue engineering

B Niemczyk-Soczynska, A Gradys, P Sajkiewicz - Polymers, 2020 - mdpi.com
… In recent decades, electrospun nanofibrous scaffolds have … attractive as scaffolds in tissue
engineering, drug delivery systems, … occurred to be a useful tool for non-viral genome editing. …

Delivery of transcription factors as modulators of cell differentiation

H Rilo-Alvarez, AM Ledo, A Vidal… - Drug Delivery and …, 2021 - Springer
delivery methods are the most common non-viral transfection systems used in gene therapy.
They … Some gene delivery nanoparticles can also be formed by physical encapsulation or …

Nanoarchitectonics is an emerging drug/gene delivery and targeting strategy-a critical review

V Karthik, S Poornima, A Vigneshwaran… - Journal of Molecular …, 2021 - Elsevier
… AgNPs as suitable materials for drug and gene delivery. AgNPs functionalized with
biodegradable polymers can be used as potential non-viral carriers in targeted drug delivery [27]. …

Advanced liposome-loaded scaffolds for therapeutic and tissue engineering applications

R Cheng, L Liu, Y Xiang, Y Lu, L Deng, H Zhang… - Biomaterials, 2020 - Elsevier
… In this review, we will mainly focus on the drug delivery … As non-viral delivery system, one of
the most popular functions … (HUVECs) on the nanofibrous scaffolds with different formulation i …

Delivery of hepatocyte growth factor mRNA from nanofibrillar scaffolds in a pig model of peripheral arterial disease

TS Zaitseva, G Yang, D Dionyssiou… - Regenerative …, 2020 - Future Medicine
Gene therapy is a powerful approach to regulate target protein expression for regenerative
applications [6]. Most commonly, it employs DNA-… of gene therapy for soft tissue regeneration. …