Human Stem Cell Based Tissue Engineering for In Vivo Cartilage Repair: A Systematic Review

W Kabir, C Di Bella, I Jo, D Gould… - Tissue Engineering Part …, 2021 - liebertpub.com
… as the biomechanical quality of neocartilage is of great functional significance. … significantly
lower in the stem cell-derived repair tissue than the microfracture-induced tissue at both 6 …

Advanced functional biomaterials for stem cell delivery in regenerative engineering and medicine

X Wang, N Rivera‐Bolanos, B Jiang… - Advanced Functional …, 2019 - Wiley Online Library
… that promises to repair or regenerate functional tissues and … of these stem cell populations
is that they are committed into … and maturation of stem cellderived cardiomyocytes and …

A realistic appraisal of the use of embryonic stem cell-based therapies for cardiac repair

M Wysoczynski, R Bolli - European heart journal, 2020 - academic.oup.com
… left ventricular (LV) function in animal models of ischaemic … labelled human embryonic stem
cell-derived cardiovascular … their stemness and commitment to the cardiovascular lineage. …

Human cardiomyocytes undergo enhanced maturation in embryonic stem cell-derived organoid transplants

F Varzideh, S Pahlavan, H Ansari, M Halvaei, S Kostin… - Biomaterials, 2019 - Elsevier
… , biochemical, and functional properties of embryonic or fetal cardiac cells … tissue-specific
stem cells by cell sorting and spatially restricted lineage commitment partially mimics in vivo

Engineered biomaterials for in situ tissue regeneration

AK Gaharwar, I Singh, A Khademhosseini - Nature Reviews Materials, 2020 - nature.com
… with bioactive cues, to guide functional restoration to the site of … are needed to obtain functional
tissues ex vivo, which are not … patch local delivery of stem-cell-derived exosomes and a …

Stem-cell-based embryo models for fundamental research and translation

J Fu, A Warmflash, MP Lutolf - Nature materials, 2021 - nature.com
… future opportunities of stem-cell-derived embryo models for … prolonged in vitro culture of
IVF human embryos has opened … for additional molecular and functional characterizations for …

[HTML][HTML] Human embryonic stem cell-derived cardiomyocytes regenerate the infarcted pig heart but induce ventricular tachyarrhythmias

R Romagnuolo, H Masoudpour, A Porta-Sánchez… - Stem Cell Reports, 2019 - cell.com
… endpoints, we also examined the functional consequences of hESC-CM transplantation,
including LV dimensions and contractile function using cardiac magnetic resonance imaging (…

[HTML][HTML] Regenerative potential of mouse embryonic stem cell-derived PDGFRα+ cardiac lineage committed cells in infarcted myocardium

SP Hong, S Song, S Lee, H Jo, HK Kim… - World Journal of Stem …, 2019 - ncbi.nlm.nih.gov
… -committed but in a morphologically and functionally immature state compared with differentiated
CMs[11]. In the present study, we investigated the regenerative … both in vitro and in vivo

Tissue-engineered human embryonic stem cell-containing cardiac patches: evaluating recellularization of decellularized matrix

C Hochman-Mendez… - … Tissue Engineering, 2020 - journals.sagepub.com
… : (1) human embryonic stem cell-derived cardiomyocytes (hESC-… to engineer human-sized
cardiac tissues and hearts in vitro. … function of cardiomyocytes derived from human embryonic

In vitro matured human pluripotent stem cellderived cardiomyocytes form grafts with enhanced structure and function in injured hearts

W Dhahri, T Sadikov Valdman, D Wilkinson, E Pereira… - Circulation, 2022 - Am Heart Assoc
… Although Herron and colleagues 27 previously reported that culture of already-committed
(≈… In our hands, attachment of already-committed hPSC-CMs onto PDMS was relatively poor …