[HTML][HTML] The promising potential of piperlongumine as an emerging therapeutics for cancer

D Parama, V Rana, S Girisa, E Verma… - … of Targeted Anti …, 2021 - ncbi.nlm.nih.gov
… ), or piplartine, is one such alkaloid isolated from Piper longum … of two types, namely, melanoma
and non-melanoma [179, 180]… PL, the amide alkaloid isolated from the roots and fruits of …

[PDF][PDF] Piperine: A review on different formulations and pharmacological activities.

MR Sharma, N Raghav - Chemistry & Biology Interface, 2021 - cbijournal.com
… Ant proliferative effects of two amides, piperine and piplartine, from Piper species. … In vivo
growth-inhibition of Sarcoma 180 by piplartine and piperine, two alkaloid amides from Piper. …

[HTML][HTML] A novel piperine analogue exerts in vivo antitumor effect by inducing oxidative, antiangiogenic and immunomodulatory actions

RC Ferreira, TM Batista, SS Duarte, DKF Silva… - Biomedicine & …, 2020 - Elsevier
Piperine, 1-piperoylpiperidine, is a simple and pungent alkaloid found in seeds of black
pepper (Piper … On the other hand, piplartine, an alkamide present in Piper species induces in …

Peppers: a “Hot” natural source for antitumor compounds

MR Cunha, MT Tavares, TB Fernandes, R Parise-Filho - Molecules, 2021 - mdpi.com
Piplartine or piperlongumine 10 is the major bioactive alkaloid extracted from the dried fruits
of the PiperPiperine 28 is the major alkaloid found in P. nigrum, the most common pepper …

Synergistic effects of methotrexate and piperine on human osteosarcoma cell lines–An in-vitro study

E Anitha, K Neevedha, A Isswariya… - National Journal of …, 2023 - search.proquest.com
Piperine (PPN) is one of those constituents isolated from Piper nigrum with amide group that
was … There are no available data on the beneficial synergistic anti-sarcoma potential of the …

Piperlongumine, a potent anticancer phytotherapeutic, induces cell cycle arrest and apoptosis in vitro and in vivo through the ROS/Akt pathway in human thyroid …

FP Kung, YP Lim, WY Chao, YS Zhang, HI Yu, TS Tai… - Cancers, 2021 - mdpi.com
… ), also known as piplartine, is an amide alkaloid isolated from long pepper, Piper longum L.
[6]. … (Figure 1), we further examined whether growth inhibition by PL led to cell cycle alteration …

[PDF][PDF] Piperine: A Savor Inducer and a Cancer Reducer

M Djaldetti - OBM Hepatology and Gastroenterology, 2021 - scholar.archive.org
… An alkaloid called piperine is the main component in black pepper that, besides … vivo
growthinhibition of Sarcoma 180 by piplartine and piperine, two alkaloid amides from Piper

Overview of piperlongumine analogues and their therapeutic potential

P Zhu, J Qian, Z Xu, C Meng, W Zhu, F Ran… - European Journal of …, 2021 - Elsevier
… ) is an amide alkaloid isolated from Piper longum L. (long piper) and other piper plants
and … analogues based on the structures of PL and piperine in a similar one-step Aldol …

[PDF][PDF] Review on Anti-tumor activity, Immunomodulatory and neuromodulatory properties of Piper longum Linn

D Sharma, A Kapri, S Kumar… - Journal of Ayurvedic and …, 2022 - ayurvedjournal.com
Piperine inhibits PMA-induced cyclooxygenase-2 expression through downregulating …
vivo growth-inhibition of Sarcoma 180 by piplartine and piperine, two alkaloid amides from Piper

Piplartine (piperlongumine), oxidative stress, and use in cancer

DP Bezerra - Cancer, 2021 - Elsevier
Piplartine, also known as piperlongumine, is an amide alkaloid that has a natural occurrence
in several Piper … by Bezerra and collaborators 64 using mice-bearing sarcoma 180 cells. …