… using conventional T cells, giving rise to iTregs [18]. … makes Helios a less reliable marker
for differentiating Treg cells. … is that BM Tregs maintain immune privilege through adenosine, …

… One of the potential therapeutic targets is the HSC niche which provides … Tregs confer
immune privilege to HSC. In summary, this work indicates that immune privilege, niche Tregs, and …

… Because maintenance of stem cell niches is important to sustaining life by promoting
tissue regeneration, we hypothesized that a critical function of T regs is to protect HFSCs from …

… , megakaryocytes, macrophages and regulatory T cells), with … multicellular network that
provides molecular cues and … of PubMed using ‘haematopoietic stem cell niche’ as a search term …

… Regulatory T cells (Tregs), a T cell population that is … that Tregs maintain a state of immune
privilege in bone marrow for the homeostasis of HSCs and other hematopoietic cells provides …

… In vivo imaging of BM has demonstrated that Tregs cluster … Our results provide mechanistic
insight into Treg regulation of … blood stem cell regulation is a defining feature of the niche with …

… niches and revealed major cellular components of niches for hematopoietic stem and progenitor
cells (… PαS cells will provide direct evidence for a role of PαS cells in HSC maintenance. …

… Regulatory T cells (Tregs) have long been appreciated as … Finally, Tregs support the unique
stem cell niches in the skin, … studies provide support for a model in which Tregs produce …

… establishment of an immune privileged niche to maintain HSC … 1 Immune cell subsets present
in the BM stem cell niche and … The BM microenvironment does not only provide HSCs with …

… homeostasis following stem-cell transplantation. We … We provide evidence that BM-Treg
are phenotypically distinct from pTreg and have differential requirements for BM niche cellular …