… In this study, we provide a novel mechanism by which marrow Tregs support the … In vivo
imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche. Nature. …

… Tregs in other lymphoid organs by 3- to 4-fold. In the BM, Tregs populate hematopoietic stem
cell (HSC) niches … and Foxp3+ Treg cells closely interact to confer immune privilege to BM …

… regulatory T cells (Tregs) have been shown to help create an … cells), immune privilege
provides additional safe harbor from … improved knowledge of stem cell immune privilege, how it is …

… niche may maintain immune privilege by: firstly, providing a physical barrier to separate
HFSCs from any infiltrating inflammatory cells, … Overall, this study points to an intricate stem cell-…

… The HSC niche provides immunosuppression and minimises … can disrupt the original stem
cell–niche interaction and force the … transplant Treg cells IL-10 The presence of Treg cells was …

… Specialized immune cells known as regulatory T cells (Tregs) … Finally, Tregs in the bone
maintain hematopoietic stem cell … sites that provide additional adaptive immune cell support to …

… the role of immune cells providing CSCs to evade tumor … The protected niche of CSCs is
provided by overactivation of … Regulatory T cells (Tregs) are a T cells-originated subset that …

… distinct niche cell types and that many defined niche cells provide more than one important
factor (Figure 2). We focus on factors produced by murine non-hematopoietic niche cells that …

… surface, providing an immune tolerance microenvironment for … distribution of Tregs in the
bone marrow osteoblast niche by … a static state to maintain the hematopoietic stem cell pool3. …

… data provided further evidence supporting skin-resident T reg … image Finally, to determine
the role of TGF-β3 produced by T reg cells in hair regeneration in vivo, we generated a T reg …