Different mutation profiles between epithelium and stroma in endometriosis and normal endometrium

K Suda, H Nakaoka, K Yoshihara, T Ishiguro… - Human …, 2019 - academic.oup.com
… 11 endometriotic stroma samples and 10 normal endometrial stroma samples between 2013
and 2017 at a … cells would be independent of each other in both normal endometrium and …

Similar characteristics of endometrial and endometriotic epithelial cells

L Konrad, J Gronbach, F Horné… - Reproductive …, 2019 - journals.sagepub.com
… We suppose that the abundance of ZEB1 in the endometrial stromal and epithelial cells
suggests that both cell types exhibit a high cellular plasticity because the human …

[HTML][HTML] Altered differentiation of endometrial mesenchymal stromal fibroblasts is associated with endometriosis susceptibility

BD McKinnon, SW Lukowski, S Mortlock… - Communications …, 2022 - nature.com
growth rates of individual cell preparations, endometriosis … For individual preparations, the
growth rates varied for both … , we used cytokeratin (green) to identify and exclude epithelial

[HTML][HTML] Epithelial–mesenchymal transition in endometriosis—when does it happen?

L Konrad, R Dietze, MA Riaz, G Scheiner-Bobis… - Journal of Clinical …, 2020 - mdpi.com
… of the eutopic endometrium of women with and without endometriosis … is independent of the
three endometriotic subtypes (ovarian, … that epithelial cells do not transform into stromal cells. …

The origin and pathogenesis of endometriosis

Y Wang, K Nicholes, IM Shih - Annual Review of Pathology …, 2020 - annualreviews.org
epithelium and stroma within the same endometriotic lesions. … individual glands and an
endometriotic cyst in the same … higher in endometriotic epithelial cells than in normal uterine

[HTML][HTML] In‑vitro models of human endometriosis

H Fan - Experimental and Therapeutic Medicine, 2020 - spandidos-publications.com
endometriotic cell lines, primary endometrial stromal cells, … reverse transcriptase to develop
individual cell lines, which … condition in which endometrial stroma and epithelium can be …

[HTML][HTML] A revised stem cell theory for the pathogenesis of endometriosis

T Maruyama - Journal of Personalized Medicine, 2022 - mdpi.com
… -initiating cells are likely to be endometrial epithelial cells … for endometriotic stroma-initiating
cells may be endometrial … is clonal and its development is independent of stroma [59]. …

New concepts on the etiology of endometriosis

FL Cousins, BD McKinnon, S Mortlock… - Journal of Obstetrics …, 2023 - Wiley Online Library
… and initiate stromal endometriosis lesions when shed into the … differentiate into endometrial
stromal cells to form endometriotic … of individual epithelial glands both within endometriotic

Epithelial mutations in endometriosis: link to ovarian cancer

SE Bulun, Y Wan, D Matei - Endocrinology, 2019 - academic.oup.com
… Unlike epithelial cells, endometriotic stromal cells are mutation … pelvic endometriotic lesions
contain endometrial stromal cells… independent reports was that histologically normal, eutopic …

The pathogenesis of endometriosis: are endometrial stem/progenitor cells involved?

AS Laganà, A Naem - Stem Cells in Reproductive Tissues and Organs …, 2022 - Springer
… and progression [19, 20], the exact origin of the endometriotic epithelial and stromal cells
is yet to be identified. To date, many hypotheses trying to identify the origin of the ectopic …