… the genetic level. Over the past several years, our understanding of the genetic factors influencing
alcohol use … Yellow indicates alcohol use, light orange indicates alcohol sensitivity and …

… factors, for example tobacco smoking and alcohol consumption are both common risk factors
for … functions in the body which render it more susceptible to other diseases and injuries, as …

… addiction, to help understand the biological mechanisms involved and which may be useful
… Smoking is influenced by genetic factors including variations in CYP2A6 and CYP2B6, …

… For men and for women we also calculated as sensitivity … individual drinking patterns to
various factors) and genetic … variants we studied are involved in many biochemical pathways…

… 7) and found that these dZip71B Mi/MB flies also displayed naive sensitivity to sedation
induced by ethanol (t 14 = 3.23, Hedge’s g = −1.54, 95% CI = −0.42 to −2.65, P = 0.006) and …

… of pathophysiological factors are specific to hepatic alcohol-… breadth of inter-individual
susceptibility to the development … the potential biological explanation linking these genetic traits …

… to mean susceptibility or liability to exposure having causal effect on susceptibility or liability
… brain regions and gene expression regulatory regions, providing biological insights into the …

… , the genetic background determine susceptibility to NAFLD … contribution of environmental
and genetic factors. Epigenetics, … In recent years, NAFLD has become a biological marker of …

… The susceptibility to develop significant alcoholrelated liver … drinking; coffee consumption;
cigarette smoking; … (HCV) infection; and a number of host genetic factors.(13) Carriage of the …

… , and epigenetic factors that also cause differences in susceptibility to liver damage …
alcohol-induced dysbiosis along with several other issues concur to increase individual susceptibility …