Vascular actions of peripheral CGRP in migraine-like photophobia in mice

BN Mason, AS Wattiez, LK Balcziak, A Kuburas… - …, 2020 - journals.sagepub.com
… light aversive behavior in mice. … Both central and peripheral CGRP administration is
sufficient to cause light … Using outbred CD1 mice, we demonstrate that CGRP and VIP induce

[HTML][HTML] Investigating migraine-like behavior using light aversion in mice

M Wang, BN Mason, LP Sowers… - Journal of visualized …, 2021 - ncbi.nlm.nih.gov
… At least for photophobia, we think this is less … of CGRP and found that mice receiving
CGRP did not have a place preference with light off in the light zone, confirming that CGRP-induced

Stimulation of posterior thalamic nuclei induces photophobic behavior in mice

LP Sowers, M Wang, BJ Rea… - … : The Journal of …, 2020 - Wiley Online Library
… with both optogenetic stimulation and acute CGRP injections … CGRP can induce migraine-like
headaches and CGRP … may integrate central and peripheral signals to cause migraine-like

PACAP induces light aversion in mice by an inheritable mechanism independent of CGRP

A Kuburas, BN Mason, B Hing, AS Wattiez… - Journal of …, 2021 - Soc Neuroscience
mice as a surrogate for migraine-like photophobia to compare … CGRP in migraine, we have
used light-aversive behavior of … shown that peripheral administration of CGRP causes light …

CGRP induces migraine-like symptoms in mice during both the active and inactive phases

AS Wattiez, OJ Gaul, A Kuburas, E Zorrilla… - The journal of headache …, 2021 - Springer
… test the validity of CGRP-induced behavioral changes in mice by … of peripheral CGRP to
induce migraine-like symptoms in mice is … Therefore, preclinical assessment of migraine-like

Photophobia in headache disorders: characteristics and potential mechanisms

Y Wang, S Wang, T Qiu, Z Xiao - Journal of Neurology, 2022 - Springer
… receptor than WT mice [104]. The CGRP-induced photophobic behavior described above
could be … CSD induces headaches through central and peripheral pathways. CSD can affect …

CGRP in animal models of migraine

AS Wattiez, M Wang, AF Russo - Calcitonin Gene-Related Peptide (CGRP …, 2019 - Springer
… sensory perceptions, such as photophobia. These models are … that CGRP actions to induce
migraine-like behavior are … ip CGRP administration induced diarrhea in C57BL/6J mice

Shared and independent roles of CGRP and PACAP in migraine pathophysiology

A Kuburas, AF Russo - The Journal of Headache and Pain, 2023 - Springer
… that infusion of CGRP can induce migraine-like attacks in … Like CGRP, PACAP also induced
photophobia and other non… glibenclamide inhibits CGRP, but not PACAP actions in mice. …

[HTML][HTML] Repetitive stress in mice causes migraine-like behaviors and CGRP-dependent hyperalgesic priming to a migraine trigger

A Avona, BN Mason, J Lackovic, N Wajahat, M Motina… - Pain, 2020 - ncbi.nlm.nih.gov
… test stress-induced priming to dural pH 7.0 in both sexes, our … of SNP is within the
peripheral compartment. Since NO freely … Behavioral evidence for photophobia and stress-related …

Photophobia and migraine outcome during treatment with galcanezumab

F Schiano di Cola, G Ceccardi, M Bolchini… - Frontiers in …, 2023 - frontiersin.org
Both the central and the peripheral effects of CGRP action … aversive behavior in mice to
CGRP, in both wild-type mice (41… injection of CGRP induces both photic sensitivity and facial …