Electroporation as a method of choice to generate genetically modified dendritic cell cancer vaccines

R Ahmed, N Sayegh, M Graciotti… - Current opinion in …, 2020 - Elsevier
… In vitro Higher expansion of cancer-specific CTLs compared … modified DC vaccine induced
a polyclonal response toward … the enhanced capacity of the transfected DCs to induce an anti-…

Vaccines as treatments for prostate cancer

I Rastogi, A Muralidhar, DG McNeel - Nature Reviews Urology, 2023 - nature.com
… to the development of prostate cancer-specific antibodies 26,27 ; … The use of this approach
showed modest induction of tumour-… dendritic cells. In principle, antigens are present in whole-…

Microbubble-mediated delivery of human adenoviruses does not elicit innate and adaptive immunity response in an immunocompetent mouse model of prostate …

F De Carlo, L Thomas, B Brooke, ET Varney… - Journal of translational …, 2019 - Springer
cancer-specific therapeutic cytokine [39] in prostate cancer. … Dendritic cells in the spleen
have been demonstrated to be … administered adenovirus resulting in the induction of IL-6, IL-12, …

Dendritic cell-based cancer vaccine production

M Rahman - Metabolomics for Personalized Vaccinology, 2024 - Elsevier
… includes the prostate cancer-specific antigen prostatic acid … -γ signaling in melanoma induces
dendritic cell (DC) tolerance … that transfecting DCs with mRNA-encoding TSAs can induce

Microbial antigen-presenting extracellular vesicles derived from genetically modified tumor cells promote antitumor activity of dendritic cells

T Ito, K Sugiura, A Hasegawa, W Ouchi, T Yoshimoto… - Pharmaceutics, 2021 - mdpi.com
… and also present in normal tissues and (ii) cancer-specific … method using rabbit anti-ESAT-6
polyclonal antibody in the … , we induced the antigen by the direct in vivo transfection using

Dendritic cells in anticancer vaccination: rationale for ex vivo loading or in vivo targeting

AV Baldin, LV Savvateeva, AV Bazhin, AA Zamyatnin Jr - Cancers, 2020 - mdpi.com
… -DC cells to induce a CTL response, they were transfected with … antigen-specific CTLs that
induce cytolysis of target cells. The … , polyclonal antigen-specific CD4 + and CD8 + T cells are …

Identification of novel cancer-specific T cell targets by dissection of successful tumour-infiltrating lymphocyte therapy

C Rius Rafael - 2019 - orca.cardiff.ac.uk
cell-based cancer immunotherapy has emerged as the biggest development in cancer treatment
since radiotherapy and is capable of inducing … thymic epithelial cells and dendritic cells. …

[PDF][PDF] Understanding the effect and mechanisms of CD40 agonist therapy on tumour growth and dendritic cell vaccination strategies

A Murgaski - 2022 - researchportal.vub.be
… therapy using αCD40, an immunogenic cell death inducing … be used to improve dendritic
cell vaccination strategies and … the T cells will kill cancer cells, releasing new cancer-specific

[引用][C] Perhaps not everyone knows that...

H Hansen - Elsevier
… Although dendritic cells pulsed with single prostate-cancer-specific antigens are known to …
et al Induction of polyclonal prostate cancer-specific CTL using dendritic cells transfected with …

Peptide vaccine from cancer-testis antigen ODF2 can potentiate the cytotoxic T lymphocyte infiltration through IL-15 in non-MSI-H colorectal cancer

R Shi, X Zhou, L Pang, M Wang, Y Li, C Chen… - Cancer Immunology …, 2023 - Springer
… to induce and expand cytotoxic T lymphocytes (CTLs) against … T lymphocytes and dendritic
cells (DCs) were cultured in GT-… cancer-specific MUC1 glycoforms may educate myeloid cells