Resveratrol as an enhancer of apoptosis in cancer: a mechanistic review

M Ashrafizadeh, S Taeb… - … -Cancer Agents in …, 2021 - ingentaconnect.com
… different cancer cell lines has confirmed that resveratrol induces apoptosis through different
Induction of sirtuin-1 signaling by resveratrol induces human chondrosarcoma cell apoptosis

An update on current and future treatment options for chondrosarcoma

IJ MacDonald, CY Lin, SJ Kuo, CM Su… - Expert Review of …, 2019 - Taylor & Francis
… by inhibiting the activity of PI3K/Akt and p38 MAPK signaling … the induction of apoptosis
and antitumor activity of resveratrol involves the activation of sirtuin 1 (Sirt1) in human CS cells […

Resveratrol in management of bone and spinal cancers

G Chen, H Xia, Z Zhang, H Yu - Natural product research, 2019 - Taylor & Francis
Chondrosarcoma (CS) is another common type of primary … Resveratrol is able to induce
apoptotic cell death and a … 3 (STAT3) signalling pathway by activating sirtuin 1 (Sirt1) (Jin …

Mechanism of resveratrol-induced programmed cell death and new drug discovery against cancer: A Review

JY Jang, E Im, ND Kim - International journal of molecular sciences, 2022 - mdpi.com
induce the formation of the death-inducing signalingresveratrol causes chondrosarcoma
cell apoptosis through SIRT1-activated NF-κB deacetylation and shows anti-chondrosarcoma

Estradiol as the Trigger of Sirtuin-1-Dependent Cell Signaling with a Potential Utility in Anti-Aging Therapies

K Karolczak, C Watala - International Journal of Molecular Sciences, 2023 - mdpi.com
inducing a highly mitotic state and resistance to apoptosis, with … was effectively prevented
by resveratrol. Maintaining the correct … The consequences of sepsis-associated cell death are …

[PDF][PDF] Protective effect of resveratrol on knee osteoarthritis and its molecular mechanisms: a recent review in preclinical and clinical trials

S Yang, M Sun, X Zhang - Frontiers in Pharmacology, 2022 - frontiersin.org
… In ethanol-induced cell death models, RES is protective at low doses (10–25µM) … signaling
pathway, RES can also modulate multiple other signaling pathways that mediate apoptosis to …

Resveratrol's anti-cancer effects through the modulation of tumor glucose metabolism

A Brockmueller, S Sameri, A Liskova, K Zhai… - Cancers, 2021 - mdpi.com
… , resveratrol-induced ER-stress leads to apoptosis of … resveratrol is the molecular signaling
pathway dependent on sirtuins (histone deacetylases) [168]. Resveratrol upregulates sirtuin 1

A pharmacological review on SIRT 1 and SIRT 2 proteins, activators, and inhibitors: Call for further research

M Nandave, R Acharjee, K Bhaduri, J Upadhyay… - International Journal of …, 2023 - Elsevier
… that resveratrol-generated apoptosis is caused by the change in the facilitated cell survival
(FAS) signaling [49]. … It induced the cell cycle arrest of glioma cells and apoptosis followed by …

Targeting Sirtuin 1 signaling pathway by ginsenosides

T Lou, Q Huang, H Su, D Zhao, X Li - Journal of Ethnopharmacology, 2021 - Elsevier
… Additionally, in cobalt chloride-induced PC12 cells and cerebral I/R injured rat models, …
SIRT1 signaling pathways, which may be related by the inhibitions of ROS generation, apoptosis, …

[HTML][HTML] Protective effects of resveratrol against 5-fluorouracil-induced oxidative stress and inflammatory responses in human keratinocytes

S Chen, N Tamaki, Y Kudo, T Tsunematsu… - Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
… Nrf2 signaling and inhibiting NF-κB signaling, respectively. … (2) 5-FU blocks DNA replication
and induces the … and activity of Nrf2, suppresses apoptosis and resistance to oxidative stress. …