Differential methylation and acetylation as the epigenetic basis of resveratrol's anticancer activity

M Farhan, MF Ullah, M Faisal, AA Farooqi… - Medicines, 2019 - mdpi.com
resveratrol and its regulation of key oncogenic signaling pathways. Additionally, the activation
of sirtuin 1, a deacetylase, by resveratrolcells, resveratrol can effectively induce apoptosis

An investigation on the effects of SIRT5 modulators on SIRT5 and cytochrome C protein expressions in K562 chronic myeloid leukemia cell line

T Ozkan, A Koc, AZ Karabay… - Journal of Faculty of …, 2022 - dergipark.org.tr
… (Cell Signaling Technology) and anti-Cytc (Cell Signalling … determined that Resveratrol
induces apoptosis of K562 cells (p… apoptosis inducing effect in K562 cells (Figure 4a and 4b). …

Resveratrol reverses endothelial colony-forming cell dysfunction in adulthood in a rat model of intrauterine growth restriction

E Guillot, A Lemay, M Allouche, S Vitorino Silva… - International Journal of …, 2023 - mdpi.com
… , in a rat model of IUGR induced by altered maternal nutrition … In this study, resveratrol
increased Sirtuin-1 expression in the … against Sirtuin-1 and eNOS (rabbit, 1:100; cell signaling) …

Resveratrol action on lipid metabolism in cancer

T Kisková, M Kassayová - International journal of molecular sciences, 2019 - mdpi.com
… Thus, resveratrol could be used as a preventive and … and signal molecules which are affected
by resveratrol during … -induced cell death after mTOR inhibitor rapamycin in glioma cancer …

Curcumin and Resveratrol: Nutraceuticals with so Much Potential for Pseudoachondroplasia and Other ER-Stress Conditions

KL Posey - Biomolecules, 2024 - mdpi.com
apoptosis-inducing factor suggest that mutant-COMP-… perception and transmission of pain
signals to the central nervous system [… that resveratrol suppresses mutant-COMP-induced pain …

SIRT1: a potential tumour biomarker and therapeutic target

B Zhao, X Li, L Zhou, Y Wang, P Shang - Journal of drug targeting, 2019 - Taylor & Francis
… by activating β2-AR signalling in cervical cancer cells. … in Burkitt lymphoma cells induced cell
apoptosis [Citation69]. … promoted the metastasis of chondrosarcoma cells by enhancing EMT…

[PDF][PDF] Protective effect of resveratrol on knee osteoarthritis and its molecular mechanisms: a recent review in preclinical and clinical trials

S Yang, M Sun, X Zhang - Frontiers in Pharmacology, 2022 - frontiersin.org
… In ethanol-induced cell death models, RES is protective at low doses (10–25µM) … signaling
pathway, RES can also modulate multiple other signaling pathways that mediate apoptosis to …

The bifunctional roles of sirtuins and their therapeutic potential in cancer

YT Lee, YJ Tan, PY Mok, AV Subramaniam… - … in Cancer and Metabolic …, 2021 - Elsevier
… but inhibits FOXO3a-induced cell death, highlighting the partial … signaling pathway [277].
RSV was also reported to reduce … in siRNA-SIRT1 transfected human chondrosarcoma (a …

MiR-128-3p mediates TNF-α-induced inflammatory responses by regulating Sirt1 expression in bone marrow mesenchymal stem cells

L Wu, G Zhang, C Guo, X Zhao, D Shen… - … and biophysical research …, 2020 - Elsevier
… Up-regulation of sirtuin 1 induced by resveratrol also … -128-3p targets sirtuin 1 to mediate
the TNF-α-induced inflammatory … gingivalis-induced inflammatory response via p38 signaling

Pharmacological targeting of heme oxygenase-1 in osteoarthritis

Y Sanada, SJO Tan, N Adachi, S Miyaki - Antioxidants, 2021 - mdpi.com
… or chemically-induced antioxidant signals prevent cartilage … suppression of apoptosis and
MMP-13 elevation induced by MIA in vivo … Thus, local HO-1 induction by resveratrol IA injection …