… protects against mitochondrial dysfunction in atherosclerosis (AS) mice with chronic unpredictable mild stress (CUMS) via SIRT1/PGC-1α/TFAM/LON signaling …

H Shi, M Sun, S Wang, F He, R Yang, Z Li… - Journal of …, 2024 - Elsevier
… Besides, resveratrol significantly increased the ATP levels … -1α/TFAM/Lon signaling pathway.
The current study possesses … signaling pathway for the treatment of chronic stress-induced

A network-based transcriptomic landscape of HepG2 cells uncovering causal gene-cytotoxicity interactions underlying drug-induced liver injury

LS Wijaya, A Gabor, IE Pot, L van de Have… - Toxicological …, 2024 - academic.oup.com
… We correlated gene coregulated networks with cell death onset and causal relationships of
Induction of sirtuin-1 signaling by resveratrol induces human chondrosarcoma cell apoptosis

Curcumin regulates autophagy through SIRT3-SOD2-ROS signaling pathway to improve quadriceps femoris muscle atrophy in KOA rat model

H Ye, Y Long, JM Yang, YL Wu, LY Dong, YB Zhong… - Scientific Reports, 2024 - nature.com
apoptosis 30 . CUR can effectively improve muscle disuse muscular atrophy by activating
the deacetylase sirtuin-1 … of CUR in KOA-induced quadriceps femoris muscle atrophy. Based …

[HTML][HTML] Aging: a cell source limiting factor in tissue engineering

M Khorraminejad-Shirazi, M Dorvash… - … journal of stem cells, 2019 - ncbi.nlm.nih.gov
cell signaling pathways that provide appropriate cell-cell … In addition, induction of
pluripotency and the process of … cardiac stem cells with rapamycin and resveratrol improves the …

Progress and promises of epigenetic drugs and epigenetic diets in cancer prevention and therapy: A clinical update

P Mondal, J Natesh, D Penta, SM Meeran - Seminars in Cancer Biology, 2022 - Elsevier
… epigenomic modulations alter cell signaling pathways and the … with apoptosis, cell cycle
arrest, as well as cause cellular … to inhibit human squamous cell carcinoma and induce cell

Emerging natural-product-based treatments for the management of osteoarthritis

ML Pérez-Lozano, A Cesaro, M Mazor, E Esteve… - Antioxidants, 2021 - mdpi.com
… and apoptosis, resveratrol has been … Resveratrol induced osteoblast differentiation by
regulating autophagy and modulating the Sirt1/Runx-2/Fox-O1 and PI3K/AKT/mTOR signaling

Phytochemicals mediate autophagy against osteoarthritis by maintaining cartilage homeostasis

Z Tian, X Zhang, M Sun - Frontiers in Pharmacology, 2021 - frontiersin.org
apoptosis by modulating autophagy-related signalinginduction of the Sirtuin-1 (SIRT-1)
pathway, thus protecting … water, and in addition, resveratrol is chemically unstable when …

New vistas in malignant mesothelioma: MicroRNA architecture and NRF2/MAPK signal transduction

M Gandhi, S Nair - Life Sciences, 2020 - Elsevier
… with differential diagnosis of chondrosarcoma. The biphasic MM … effects of resveratrol in
combination with cisplatin in human … and sirtuin 1 (SIRT1) in pemetrexed-induced apoptosis in …

Role of plant-derived active constituents in cancer treatment and their mechanisms of action

AW Khan, M Farooq, M Haseeb, S Choi - Cells, 2022 - mdpi.com
… cancers by inducing DNA damage and AMPK signaling and … Furthermore, the apoptotic
cell death is induced by these … role in the anticancer activities of resveratrol. For this purpose, …

Overview of MMP-13 as a promising target for the treatment of osteoarthritis

Q Hu, M Ecker - International journal of molecular sciences, 2021 - mdpi.com
apoptosis and ECM degradation in resveratrol-treated OA chondrocytes via the Wnt/β-catenin
signaling … by siRNA in SW 1353 human chondrosarcoma cells induced by IL-1β leads to a …