Dysbiosis in inflammatory bowel disease: pathogenic role and potential therapeutic targets

PT Santana, SLB Rosas, BE Ribeiro, Y Marinho… - International journal of …, 2022 - mdpi.com
… the gut microbiota has become a focus of major interest in the study of inflammatory bowel
disease (IBD) pathogenesis. … of several gut microbiome abnormalities in patients with Crohn’s …

Extraintestinal manifestations in inflammatory bowel diseaseepidemiology, genetics, and pathogenesis

T Greuter, SR Vavricka - Expert review of gastroenterology & …, 2019 - Taylor & Francis
… classical EIM focusing on epidemiology, genetics, and pathogenesis, highlighting recent
advances in the understanding of EIM. We further discuss treatment-induced immunological …

Revisiting inflammatory bowel disease: pathology, treatments, challenges and emerging therapeutics including drug leads from natural products

K Yeshi, R Ruscher, L Hunter, NL Daly… - Journal of clinical …, 2020 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic and life-long disease characterized by
gastrointestinal tract inflammation. It is caused by the interplay of the host’s genetic predisposition …

[HTML][HTML] Inflammatory bowel diseases and spondyloarthropathies: from pathogenesis to treatment

GE Fragoulis, C Liava, D Daoussis… - World journal of …, 2019 - ncbi.nlm.nih.gov
… uveitis, psoriasis and inflammatory bowel disease (IBD) are frequently observed in the
setting of SpA and are, in fact, part of the SpA classification criteria. Bowel involvement seems to …

[PDF][PDF] Therapeutic opportunities in inflammatory bowel disease: mechanistic dissection of host-microbiome relationships

DR Plichta, DB Graham, S Subramanian, RJ Xavier - Cell, 2019 - cell.com
… The current understanding of inflammatory bowel disease (IBD) pathogenesis implicates
a complex interaction between host genetics, host immunity, microbiome, and environmental …

Changing global epidemiology of inflammatory bowel diseases: sustaining health care delivery into the 21st century

AN Ananthakrishnan, GG Kaplan, SC Ng - Clinical Gastroenterology and …, 2020 - Elsevier
… and microbiome on disease pathogenesis and have offered opportunities for disease prevention
by … to provide globally sustainable inflammatory bowel disease care in the 21st century. …

The epidemiology of inflammatory bowel disease: East meets west

WY Mak, M Zhao, SC Ng… - Journal of gastroenterology …, 2020 - Wiley Online Library
incidence of inflammatory bowel diseases (IBD) in East has risen over the past decade to
become a global disease. … of the estimated prevalence of inflammatory bowel diseases (IBD) …

The microbiome in inflammatory bowel diseases: from pathogenesis to therapy

S Liu, W Zhao, P Lan, X Mou - Protein & cell, 2021 - academic.oup.com
Inflammatory bowel disease (IBD) has become a global disease with accelerating incidence
worldwide in the 21st century while its accurate etiology remains unclear. In the past decade…

History of inflammatory bowel diseases

GC Actis, R Pellicano, S Fagoonee… - Journal of clinical …, 2019 - mdpi.com
… and therapeutic opportunities. The factors previously mentioned as associated with IBD,
ie, the environment, the genes, the microbiota, and the immune systems, may all be critically …

Depression and anxiety in inflammatory bowel disease: epidemiology, mechanisms and treatment

TH Bisgaard, KH Allin, L Keefer… - Nature reviews …, 2022 - nature.com
… Depression and anxiety are common comorbidities in inflammatory bowel disease (IBD),
but the prevalence varies across studies owing to heterogeneity in study populations and …