managing the adverse events caused by anti‐TNF therapy in inflammatory bowel disease

UN Shivaji, CL Sharratt, T Thomas… - … & therapeutics, 2019 - Wiley Online Library
… These drugs work on a common pathway of blocking TNFα, a pro-inflammatory cytokine …
The incidence and prevalence of anaemia was approximately 19% and 28%, respectively, …

Very early onset inflammatory bowel disease: a clinical approach with a focus on the role of genetics and underlying immune deficiencies

J Ouahed, E Spencer, D Kotlarz… - Inflammatory bowel …, 2020 - academic.oup.com
… Very early onset inflammatory bowel disease (VEO-IBD) is defined as IBD presenting before
… In addition, patients with VEO-IBD have a higher incidence of inflammatory bowel disease

[HTML][HTML] Roles of autophagy-related genes in the pathogenesis of inflammatory bowel disease

S Kim, HS Eun, EK Jo - Cells, 2019 - mdpi.com
diseases such as inflammatory bowel disease (IBD). IBD is a complicated inflammatory colitis
disorder; Crohn’s disease and … the development of new therapeutic opportunities for IBD. …

A State-of-the-Art Review of New and Emerging Therapies for the Treatment of IBD

KO Chudy-Onwugaje, KE Christian… - Inflammatory bowel …, 2019 - academic.oup.com
therapies targeting several immune pathways have been developed for the treatment of
patients with inflammatory bowel diseasetreatment for moderate to severe Crohn’s disease and …

[HTML][HTML] Pathophysiology of inflammatory bowel disease: innate immune system

A Saez, B Herrero-Fernandez, R Gomez-Bris… - International journal of …, 2023 - mdpi.com
… an inflammatory biomarker [256], are reduced in patients with inflammatory bowel diseases,
… levels are increased in patients with inflammatory bowel disease when compared to control …

[HTML][HTML] JAK-STAT pathway regulation of intestinal permeability: pathogenic roles and therapeutic opportunities in inflammatory bowel disease

H Lei, MS Crawford, DF McCole - Pharmaceuticals, 2021 - mdpi.com
… that trigger disease activity in chronic inflammatory bowel disease (IBD). Disruption of the
epithelial barrier, in the form of increased intestinal permeability, is a feature of IBD and other …

JAK–STAT pathway targeting for the treatment of inflammatory bowel disease

A Salas, C Hernandez-Rocha, M Duijvestein… - Nature reviews …, 2020 - nature.com
intestinal homeostasis and inflammatory bowel disease. The cytosolic domain of the
transmembrane receptors for these factors include tyrosine residues (Y) that act as docking sites for …

Induction and maintenance treatment of inflammatory bowel disease: a comprehensive review

DY Jeong, S Kim, MJ Son, CY Son, JY Kim… - Autoimmunity …, 2019 - Elsevier
… Ulcerative colitis (UC) and Crohn's disease (CD) are the two major types of inflammatory
bowel disease (IBD). We conducted a comprehensive review of meta-analyses to summarize …

Comorbidities in inflammatory bowel disease: a call for action

M Argollo, D Gilardi, C Peyrin-Biroulet… - The lancet …, 2019 - thelancet.com
Inflammatory bowel disease (IBD) is a chronic systemic inflammatory condition. Previously,
the focus has been on extraintestinal manifestations of IBD, including arthritis, psoriasis, and …

Insights into the epidemiology, pathogenesis, and therapeutics of nonalcoholic fatty liver diseases

Y Yu, J Cai, Z She, H Li - Advanced Science, 2019 - Wiley Online Library
… , and many other diseases. Over the past few decades, countless studies focusing on the
investigation of noninvasive diagnosis, pathogenesis, and therapeutics have revealed different …