Age-related decline in the resistance of mice to bacterial infection and in LPS/TLR4 pathway-dependent neutrophil responses

…, PA Machin, L Crossland, C Pantarelli… - Frontiers in …, 2022 - frontiersin.org
… (16), or clear Candida albicans after intravenous infection, leading to … into the effects of
organismal age on neutrophil function, … an age-related decline in murine neutrophil function that is …

Glutathione reductase promotes fungal clearance and suppresses inflammation during systemic Candida albicans infection in mice

VY Kim, A Batty, J Li, SG Kirk, SA Crowell… - The Journal of …, 2019 - journals.aai.org
… a role in immunological functions outside of neutrophils during … Previously, we have studied
the effects of Gsr deficiency on … Neutrophil and macrophage respiratory burst ex vivo were …

A metabolite from commensal Candida albicans enhances the bactericidal activity of macrophages and protects against sepsis

P Gu, R Liu, Q Yang, L Xie, R Wei, J Li, F Mei… - Cellular & Molecular …, 2023 - nature.com
… systematically evaluated the impact of phenylpyruvate (PPA) derived from commensal C. …
The cells suspended between Histopaque 1119 and Histopaque 1077 were murine neutrophils

[PDF][PDF] EphA2 is a neutrophil receptor for Candida albicans that stimulates antifungal activity during oropharyngeal infection

M Swidergall, NV Solis, Z Wang, QT Phan, ME Marshall… - Cell reports, 2019 - cell.com
… expressed by murine neutrophils, we stained BM neutrophils with … albicans, we analyzed
whether it influences the expression … , monocytes, and macrophages, which trigger intracellular …

Natural variation in clinical isolates of Candida albicans modulates neutrophil responses

M Shankar, TL Lo, A Traven - Msphere, 2020 - Am Soc Microbiol
impact of natural variation and phenotypic divergence in C. … macrophages and human gut
epithelial cell lines (26) and the … how P94015 behaves with mouse neutrophils. Keeping these …

The Dual Function of the Fungal Toxin Candidalysin during Candida albicansMacrophage Interaction and Virulence

A König, B Hube, L Kasper - Toxins, 2020 - mdpi.com
… in human and murine macrophages and murine bone marrow… -1β release in murine kidneys
and neutrophil recruitment [30,… is likely related to immunopathological effects [30]. Similarly, …

The protective effect of inflammatory monocytes during systemic C. albicans infection is dependent on collaboration between C-type lectin-like receptors

A Thompson, LC Davies, CT Liao… - PLoS …, 2019 - journals.plos.org
… Mice were age and gender matched for experiments. Female … hi monocytes/macrophages
and neutrophils in the kidneys of … murine neutrophils, or that dependence on these CLRs for …

The impact of ageing on monocytes and macrophages

RPH De Maeyer, ES Chambers - Immunology letters, 2021 - Elsevier
… apoptotic neutrophils, adversely affecting inflammatory responses. Candida albicans challenge
… The focus of many aged mouse studies has been on macrophages so the information on …

TRAF1 suppresses antifungal immunity through CXCL1-mediated neutrophil recruitment during Candida albicans intradermal infection

W Bai, Q Wang, Z Deng, T Li, H Xiao, Z Wu - Cell Communication and …, 2020 - Springer
Neutrophils and macrophages are the principal innate immune … In the present study, we
established a mouse model of C. … impact of TRAF1 on fungal clearance at the early stage of C. …

Candida albicans Shields the Periodontal Killer Porphyromonas gingivalis from Recognition by the Host Immune System and Supports the Bacterial Infection of …

D Bartnicka, M Gonzalez-Gonzalez, J Sykut… - International Journal of …, 2020 - mdpi.com
… -existence influenced host immunity by attenuating macrophage … The monocytes and
neutrophils found in abundance in the … Our current in vivo murine model study supported our initial …