[HTML][HTML] MicroRNA-21 inhibition suppresses alveolar M2 macrophages in an ovalbumin-induced allergic asthma mice model
… M2 macrophage inhalation restored AHR and eosinophilic airway inflammation in the
miR-21 antagomir-treated mice. Moreover, anti-miR-21 antagomir transfection decreased the …
miR-21 antagomir-treated mice. Moreover, anti-miR-21 antagomir transfection decreased the …
[HTML][HTML] MicroRNA-21 inhibition attenuates airway inflammation and remodelling by modulating the transforming growth factor β–Smad7 pathway
J Hur, CK Rhee, SY Lee, YK Kim… - The Korean Journal of …, 2021 - ncbi.nlm.nih.gov
… inhibition attenuated airway inflammation and airway remodelling in this mouse model of
OVA-induced chronic allergic … chronic asthma model that inhibition of miR-126 by antagomir did …
OVA-induced chronic allergic … chronic asthma model that inhibition of miR-126 by antagomir did …
[HTML][HTML] MicroRNA-21 released from mast cells-derived extracellular vesicles drives asthma in mice by potentiating airway inflammation and oxidative stress
Y Zou, Q Zhou, Y Zhang - American journal of translational …, 2021 - ncbi.nlm.nih.gov
… of the asthma mouse model, we stained the lung tissues of the mice using HE staining, …
Finally, we identified the effects of miR-21 and DDAH1 inhibition on asthmatic mice by HE …
Finally, we identified the effects of miR-21 and DDAH1 inhibition on asthmatic mice by HE …
MicroRNA-21 Promotes Allergic Airway Inflammation and AHR and Inhibits Mesenchymal Stem Cell Migration in Cockroach Allergen Induced Asthma Model
T Cheng, Q Mei, L Chen, F Zeng - 2021 - researchsquare.com
… -21-speci c antagomir or the PI3K inhibitor LY294002 reduced PI3K activity … a mouse model
of asthma [45]. In line herewith, we found that suppression of miR-21 can ameliorate allergic …
of asthma [45]. In line herewith, we found that suppression of miR-21 can ameliorate allergic …
A microRNA-21–mediated SATB1/S100A9/NF-κB axis promotes chronic obstructive pulmonary disease pathogenesis
… exposed mice were treated with a miR-21–specific antagomir… CS exposure reduced
lung SATB1 in a mouse model of COPD, … was inhibited with an miR-21–specific inhibitor (antagomir, …
lung SATB1 in a mouse model of COPD, … was inhibited with an miR-21–specific inhibitor (antagomir, …
MicroRNAs: potential biomarkers and targets of therapy in allergic diseases?
K Specjalski, E Jassem - Archivum immunologiae et therapiae …, 2019 - Springer
… both animal models and human studies on asthma and allergic rhinitis. On the contrary, their
increased levels inhibit the expression of various inflammatory … led to amelioration of rhinitis …
increased levels inhibit the expression of various inflammatory … led to amelioration of rhinitis …
Effects of antagomiRs on different lung diseases in human, cellular, and animal models
… antagoMiR upon viral and bacterial pneumonia. They concluded that miR-155 antagomiR
ameliorated … -155-5p with a specific antagomiR resulted in specific inhibition in vivo, it was not …
ameliorated … -155-5p with a specific antagomiR resulted in specific inhibition in vivo, it was not …
MicroRNA-21-5p promotes mucosal type 2 inflammation via regulating GLP1R/IL-33 signaling in chronic rhinosinusitis with nasal polyps
G Luan, M Wang, J Yuan, X Bu, Y Wang, S Ying… - Journal of Allergy and …, 2022 - Elsevier
… The eosinophilic CRSwNP murine model used in the present … antagomir could suppress
the development of allergic airway … asthma model, miR-21 inhibitor–treated mice had both anti-…
the development of allergic airway … asthma model, miR-21 inhibitor–treated mice had both anti-…
[HTML][HTML] Evaluation of the Possible Role of miRNAs in Chemical Allergen Potency
… animal models blocking of CTLA-4 stimulated a much severe allergic reaction and inflammation
… increases in the expression of CTLA-4 ameliorated the symptoms of allergic pulmonary …
… increases in the expression of CTLA-4 ameliorated the symptoms of allergic pulmonary …
[HTML][HTML] MiRNA-21 Regulates Bronchial Epithelial Cell Proliferation by Activating Tgfβ1/Smad Signaling Pathway and Its Correlation with Asthma Severity in Children
Y Kang, M Bai, L Deng, L Fan… - Iranian Journal of Public …, 2021 - ncbi.nlm.nih.gov
… in mouse heart. In this research, the bronchial epithelial cells were activated and inhibited
by … Hence, we made further plans to carry out in vivo experiments in mouse models in future …
by … Hence, we made further plans to carry out in vivo experiments in mouse models in future …