Targeting respiratory diseases using miRNA inhibitor based nanotherapeutics: Current status and future perspectives
… inhibited the invasion of cancer cells, development of orthotopic lung tumors and metastases
in a mouse model … that the inhibition of elevated miR-570-3p using an antagomiR restored …
in a mouse model … that the inhibition of elevated miR-570-3p using an antagomiR restored …
The interaction network of MicroRNAs with cytokines and signaling pathways in allergic asthma
… MicroRNA-21 is up-regulated in allergic airway inflammation and regulates IL-12p35 …
Inhibition of MicroRNA-21 by an antagomir ameliorates allergic inflammation in a mouse model of …
Inhibition of MicroRNA-21 by an antagomir ameliorates allergic inflammation in a mouse model of …
[PDF][PDF] Evaluation of the Possible Role of miRNAs in the Chemical Allergen Potency Short title: The roles of miRNAs in the allergy
… in animal models blocking of CTLA-4 stimulated a much severe … of CTLA-4 ameliorated the
symptoms of allergic pulmonary … MicroRNA-21 expression in neonatal blood associated with …
symptoms of allergic pulmonary … MicroRNA-21 expression in neonatal blood associated with …
[HTML][HTML] miR-21 negatively regulates the PTEN-PI3K-Akt-mTOR signaling pathway in Crohn's disease by altering immune tolerance and epithelial-mesenchymal …
Z Wang, H Zhou, F Cheng, Z Zhang… - Discovery …, 2022 - discoverymedicine.com
… with a miR-21-5p inhibitor antagomiR-21had the opposite effect. … In our in-vivo study,
upregulation of miR-21 inhibited the … -21 inhibitor and chronic colitis of animal models treated with …
upregulation of miR-21 inhibited the … -21 inhibitor and chronic colitis of animal models treated with …
[HTML][HTML] Role of microRNAs in type 2 diseases and allergen-specific immunotherapy
CA Jakwerth, H Kitzberger, D Pogorelov, A Müller… - … in Allergy, 2022 - frontiersin.org
… In a miR-155 knockout mouse model, mice tended to … severity of allergic asthma caused by
miR-3162-3p antagomir by … symptoms including airway inflammation and BHR, inhibited Th2 …
miR-3162-3p antagomir by … symptoms including airway inflammation and BHR, inhibited Th2 …
MiR-223-3p regulates the eosinophil degranulation and enhances the inflammation in allergic rhinitis by targeting FBXW7
S Wu, Z Wang, Y Zhu, X Zhu, L Guo, Y Fu… - International …, 2023 - Elsevier
… -223-3p antagomir group, 20 μl of miR-223-3p agomir and antagomir was instilled nasally …
To evaluate whether FBXW7 can inhibit inflammation in a murine model of AR, we performed …
To evaluate whether FBXW7 can inhibit inflammation in a murine model of AR, we performed …
MicroRNA targets for asthma therapy
SC Ramelli, WT Gerthoffer - Lung Inflammation in Health and Disease …, 2021 - Springer
… -inflammatory agents. Numerous studies have established efficacy of targeting pro-inflammatory
microRNAs in mouse models … and inhaled corticosteroids to inhibit inflammation. Yet up …
microRNAs in mouse models … and inhaled corticosteroids to inhibit inflammation. Yet up …
MiR-135b alleviates airway inflammation in asthmatic children and experimental mice with asthma via regulating CXCL12
Y Liu, SG Huo, L Xu, YY Che, SY Jiang… - Immunological …, 2022 - Taylor & Francis
… -135a can alleviate inflammation in OVA-induced allergic rhinitis in mice via targeting …
Inhibition of MicroRNA-21 by an antagomir ameliorates allergic inflammation in a mouse model …
Inhibition of MicroRNA-21 by an antagomir ameliorates allergic inflammation in a mouse model …
Upregulation of miR-155 regulates group 2 innate lymphoid cells by targeting c-maf in allergic rhinitis
Y Zhu, Y Liu, X Zhu, Z Wang, M Wang - European Journal of Pharmacology, 2020 - Elsevier
… of miR-155 in AR patients and mouse model. We found that … inflammatory cell infiltration of
eosinophils, which was significantly ameliorated in the modeled mice with miR-155 antagomir …
eosinophils, which was significantly ameliorated in the modeled mice with miR-155 antagomir …
Divergent Roles of miR-3162-3p in Pulmonary Inflammation in Normal and Asthmatic Mice as well as Antagonism of miR-3162-3p in Asthma Treatment
J Liu, Y Chen, F Zhang, X Peng, X Mao, W Lu… - … Archives of Allergy and …, 2020 - karger.com
… The anti-inflammatory effects of the miR-3162-3p antagomir … with the ameliorated airway
hyperresponsiveness. Besides, … In animal models of asthma, some drugs targeting the Wnt/β-…
hyperresponsiveness. Besides, … In animal models of asthma, some drugs targeting the Wnt/β-…