Emerging advances of non-coding RNAs and competitive endogenous RNA regulatory networks in asthma

X Wang, H Chen, J Liu, L Gai, X Yan, Z Guo, F Liu - Bioengineered, 2021 - Taylor & Francis
… level of endothelial miR-1 inhibited airway eosinophil proliferation and allergic airway …
inflammation in an M2-like macrophage-related cockroach allergen extract-induced mouse models

Drug regulation of microRNA

AE Abaturov, VL Babуch - CHILDS HEALTH, 2023 - childshealth.zaslavsky.com.ua
inhibitors: anti-miRNA oligonucleotides, miRNA traps, miRNA mimics that prevent miRNA
binding; peptide nucleic acids, small-molecule inhibitors… of the inflammatory response, allergic

The cell type–specific functions of miR-21 in cardiovascular diseases

B Dai, F Wang, X Nie, H Du, Y Zhao, Z Yin, H Li… - Frontiers in …, 2020 - frontiersin.org
… Green lines: in hypertension, miR-21 enhances MT-CYTB mRNA translation in the
mitochondria to inhibit hypertrophy. Pink lines: in HF, exosomal miR-21 suppresses the PTEN/AKT …

Alarmins and MicroRNAs, a new axis in the genesis of respiratory diseases: possible therapeutic implications

A Allegra, G Murdaca, L Gammeri, R Ettari… - International Journal of …, 2023 - mdpi.com
… Interestingly, an airway increases in mmu-miRNA-30a-3p inhibited HMGB1 and RUNX2
expression and reduced airway eosinophilia in an experimental animal model [135]. Therefore, …

Therapeutic approaches targeting miRNA in systemic lupus erythematosus

S Hiramatsu-Asano, J Wada - Acta Medica Okayama, 2022 - ousar.lib.okayama-u.ac.jp
… , and a pristine-induced lupus mouse model (C57BL/6 or BALB/c mice). Parts of agomir,
mimic, and antagomir … This oral miR-155 inhibitor reduced not only miR-155 but also TNFα in a …

Modes of action and diagnostic value of miRNAs in sepsis

N Antonakos, C Gilbert, C Theroude… - Frontiers in …, 2022 - frontiersin.org
… A miR-143-3p inhibitor increases ACE2 and decreases inflammatory cytokines and … used
to decrease lung inflammation involved in ARDS. In a mouse model of mycoplasma pneumonia…

MicroRNA dysregulation and therapeutic opportunities in esophageal diseases

GE Markey, CL Donohoe… - American Journal …, 2023 - journals.physiology.org
… patients with EoE to proton pump inhibitors (PPIs) found miR-223 … that an antagomir targeting
miR-223 in a mouse model of … MicroRNA-21 is up-regulated in allergic airway inflammation

Allergic and non-allergic asthma: Translational research in immunology

E Boberg - 2022 - gupea.ub.gu.se
… For example, inhibition of miR-126 with an antagomiR, ie, a … In summary, studies in murine
models of asthma and in humans … Mouse models in this thesis was used to study the ongoing …

miRNA-mediated control of B cell responses in immunity and SLE

SL Schell, ZSM Rahman - Frontiers in immunology, 2021 - frontiersin.org
… lentiviral or genetic), miRNA antagomir administration, or knockouts of … those that have been
studied in mouse models (Figure 4). … miR-873 inhibition could modestly reduce autoantibody …

The role of microRNAs in development of colitis-associated colorectal cancer

M Bocchetti, MG Ferraro, F Ricciardiello… - International Journal of …, 2021 - mdpi.com
… /DSS-induced CRC mouse models produced a higher grade … Applying nicotine as a treatment
agent could ameliorate UC … the antagomir miR-155 alleviated DSS-induced colitis in mice