MicroRNA miR-155-5p knockdown attenuates Angiostrongylus cantonensis-induced eosinophilic meningitis by downregulating MMP9 and TSLP proteins
X Zhou, J Zhang, J Liu, J Guo, Y Wei, J Li, P He… - International Journal for …, 2021 - Elsevier
… knockdown lentivirus successfully ameliorated brain injury and … dynamic fluctuations in mouse
models compared with in tissues … miR-155-5p agomir and antagomir in microglias for 24 h. …
models compared with in tissues … miR-155-5p agomir and antagomir in microglias for 24 h. …
MicroRNAs as therapeutic targets in cardiovascular disease
B Laggerbauer, S Engelhardt - The Journal of clinical …, 2022 - Am Soc Clin Investig
… miR-132/-212 cluster or an antagomir against miR-132-3p … with cardiac inflammation or
respective animal models (70, 91)… miR-155 inhibition ameliorates cardiac inflammation in mice (…
respective animal models (70, 91)… miR-155 inhibition ameliorates cardiac inflammation in mice (…
Epigenetic targets for oligonucleotide therapies of pulmonary arterial hypertension
W Gerthoffer - International Journal of Molecular Sciences, 2020 - mdpi.com
… on small molecule HDAC inhibitors in animal models of PAH, … and reversal trials in animal
models showing that therapeutic … compartment to ameliorate vascular inflammation, vascular …
models showing that therapeutic … compartment to ameliorate vascular inflammation, vascular …
Inhibiting miR-129-5p alleviates inflammation and modulates autophagy by targeting ATG14 in fungal keratitis
J Lin, Y Lin, Y Huang, J Hu - Experimental Eye Research, 2021 - Elsevier
… , we established a keratitis mouse model infected with Fusarium … -129-5p antagomir on
inflammation in experimental Fusarium … , the inhibition of miR-129-5p in a mouse FK model can …
inflammation in experimental Fusarium … , the inhibition of miR-129-5p in a mouse FK model can …
Promising roles of combined therapy based on immune response and iron metabolism in systemic lupus erythematosus
Z Xing, S Gao, A Zheng, C Tong, Y Fang… - International …, 2024 - Elsevier
… that BDH2 was the target gene of microRNA-21 (miR-21). By … Antagomir-21, a miR-21
inhibitor, may prevent organ injury … , through inhibition of ferroptosis, resulting in amelioration of …
inhibitor, may prevent organ injury … , through inhibition of ferroptosis, resulting in amelioration of …
Immune Repertoire and Advancements in Nanotherapeutics for the Impediment of Severe Steroid Resistant Asthma (SSR)
NM Beeraka, R Zhou, X Wang… - International Journal …, 2022 - Taylor & Francis
… -21 is an overexpressed gene in mouse models but the miR-21 … administration of
antagomiR-21, a miR-21 inhibitor, which … -asthmatic formulation can ameliorate the …
antagomiR-21, a miR-21 inhibitor, which … -asthmatic formulation can ameliorate the …
Thymoquinone modulates the expression of sepsis‑related microRNAs in a CLP model
KM Alkharfy, A Ahmad, BL Jan… - Experimental and …, 2022 - spandidos-publications.com
… levels of apoptotic death in animal models of sepsis following … Inhibition of miR-27a has
been shown to downregulate the … CLP model rats, thus indicating its ability to ameliorate the …
been shown to downregulate the … CLP model rats, thus indicating its ability to ameliorate the …
Differentially expressed miRNAs in ulcerative colitis and Crohn's disease
R Yarani, A Shojaeian, O Palasca… - Frontiers in …, 2022 - frontiersin.org
… cells in the UC mouse model (78). The miR-21-5p knockout … of miR-30d-5p mimic ameliorates
experimental autoimmune … Polyphenolic red wine extract (WE) inhibited inflammation in …
experimental autoimmune … Polyphenolic red wine extract (WE) inhibited inflammation in …
The roles of the gut microbiota–miRNA interaction in the host pathophysiology
M Li, WD Chen, YD Wang - Molecular Medicine, 2020 - Springer
… to ameliorate DSS-induced colonic inflammation by … : ┴ inhibition; → induction; ↑ up-regulation;
↓ down-regulation. The figure is referring to the known mechanisms in animal models …
↓ down-regulation. The figure is referring to the known mechanisms in animal models …
Alpha-1 antitrypsin—a target for microRNA-based therapeutic development for cystic fibrosis
AMD Hunt, AMA Glasgow, H Humphreys… - International journal of …, 2020 - mdpi.com
… when NE activity is inhibited by the serine protease inhibitor, … enhanced bacterial clearance
in murine models infected with P. … Once delivered inside a cell, an antagomir can bind to and …
in murine models infected with P. … Once delivered inside a cell, an antagomir can bind to and …