Interactions between the MicroRNAs and microbiota in cancer development: Roles and therapeutic opportunities

A Allegra, C Musolino, A Tonacci, G Pioggia… - Cancers, 2020 - mdpi.com
… and seems to be a promising approach for antagomir-guided approaches as therapeutic
agents. … Butyrate-caused p21 protein expression is inhibited by administration of a miRNA-106b …

MicroRNA cross-involvement in acne vulgaris and hidradenitis suppurativa: a literature review

F Borgia, L Peterle, P Custurone, M Vaccaro… - International Journal of …, 2022 - mdpi.com
… The inhibition of miR-21 in mice models results in the inhibition of TH17 cell-… antagomiR
or miR-146 agomiR appears to be a promising therapeutic approach to inhibit the inflammatory

MicroRNAs as innovative biomarkers for inflammatory bowel disease and prediction of colorectal cancer

L Masi, I Capobianco, C Magrì, I Marafini… - International Journal of …, 2022 - mdpi.com
… levels of NLRP3 and inflammation during a murine model of … products to ameliorate
DSS-induced colonic inflammation by … A recent study [60] reported that a so-called antagomir

MicroRNAs modulate neuroinflammation after intracerebral hemorrhage: Prospects for new therapy

S Xia, Y Zheng, F Yan, G Chen - Frontiers in Immunology, 2022 - frontiersin.org
Inhibition of let7c by antagomir decreases perihematomal … , reduced BBB permeability,
ameliorated brain edema, alleviated … Microrna-21 and microrna-146a negatively regulate the …

MicroRNAs as T lymphocyte regulators in multiple sclerosis

L Wang, Y Liang - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
… of Tregs in EAE mice can inhibit the migration and infiltration of mouse autoreactive T …
application of miRNA agomir/antagomir drugs. (ii) As most animal studies of miRNA therapeutic …

Mesenchymal stem cell-derived extracellular vesicles in tissue regeneration

B Zhang, X Tian, J Hao, G Xu… - Cell transplantation, 2020 - journals.sagepub.com
… pulmonary morphology, ameliorate pulmonary fibrosis and … in a hyperoxia-induced
BPD mouse model. Further RNA sequencing and … Intra-articular injection of antagomir-miRNA-100-5p …

ncRNAs in type-2 immunity

R Guidi, CJ Wedeles, MS Wilson - Non-coding RNA, 2020 - mdpi.com
… or in animal models of type-2 disease (including allergic … -126a-3p inhibition on the allergic
asthma models is due to … where inhibition of miR-126a-3p enhances, rather than inhibit, …

[HTML][HTML] Porcine circovirus type 2 ORF5 induces an inflammatory response by up-regulating miR-21 levels through targeting nuclear ssc-miR-30d

C Li, K Yang, H Song, C Xia, Q Wu, J Zhu, W Liu, T Gao… - Virus Research, 2024 - Elsevier
… Functionally, we found that miR-30d inhibited the levels of miR-21 and inflammatory cytokines
in cells. Mechanistically, we demonstrated that ORF5 inhibits miR-30d expression levels …

The role of microRNAs in diseases and related signaling pathways

A Vaghf, B Khansarinejad, E Ghaznavi-Rad… - Molecular Biology …, 2022 - Springer
… ) pathways are implicated in the inhibition of the NF-kB … 5p ameliorates pancreatic β-cell
function by inhibiting the JNK signaling pathway via targeting DACT1 in the T2DM animal model […

Iron-dependent epigenetic modulation promotes pathogenic T cell differentiation in lupus

X Gao, Y Song, J Wu, S Lu, X Min, L Liu… - The Journal of …, 2022 - Am Soc Clin Investig
… and murine models, the authors demonstrated that miR-21 was overexpressed in lupus T
cells and inhibited 3-… of Tfh cells inhibited by Antagomir-21 to levels equivalent to those of the …