[HTML][HTML] Iron-dependent epigenetic modulation promotes pathogenic T cell differentiation in lupus

X Gao, Y Song, J Wu, S Lu, X Min, L Liu… - The Journal of …, 2022 - Am Soc Clin Investig
… and murine models, the authors demonstrated that miR-21 was overexpressed in lupus T
cells and inhibited 3-… of Tfh cells inhibited by Antagomir-21 to levels equivalent to those of the …

microRNAs in cardiovascular disease: small molecules but big roles

B Yan, H Wang, Y Tan, W Fu - Current topics in medicinal …, 2019 - ingentaconnect.com
… , animal models and chemical inhibitors; however… antagomiR-155 attenuates the atherosclerotic
plaques of aortic roots and decreases inflammatory response in the ApoE-/mouse model

Trans-Resveratrol Mitigates Mir-204-3p Mediated Progression of Allergic Rhinitis by Regulating Egln3/Hif-1α/Il33/St2 Signalling Pathway

R Huang, W Mao, F Chen, B Wang, D Luo, Y Li… - Available at SSRN … - papers.ssrn.com
… Resveratrol may ameliorate rheumatoid 840 … targets, microRNA-21 and microRNA-140, are
potential biomarkers … nasal mucosa in normoxic and hypoxic mice models. A-2: Transmission …

[HTML][HTML] Sophorae tonkinensis radix polysaccharide attenuates acetaminophen-induced liver injury by regulating the miR-140-5p-related antioxidant mechanism

L Cai, L Xu, K Shen, Q Wang, R Ni, X Xu… - Journal of Traditional and …, 2024 - Elsevier
ameliorate lung injury by inhibiting inflammation and oxidative … -140-5p, agomir-140-5p +
STRP1 and antagomir-140-5p + … we created an APAP-induced mouse model of liver injury and …

[HTML][HTML] Role of noncoding RNAs in orthodontic tooth movement: new insights into periodontium remodeling

Y Chen, C Zhang - Journal of Translational Medicine, 2023 - Springer
… In a mouse model, miR-21 promoted RANKL-mediated osteoclast differentiation by targeting
the 3′UTR of PDCD4. It relieved c-Fos inhibition and led to a temporary reduction in bone …

Epigenetic Targets for Oligonucleotide Therapies

W Gerthoffer - 2020 - preprints.org
… and in animal models of PAH, but no knowledge of inflammatoryinflammation and that HDAC
inhibitors be anti-inflammatory … compartment to ameliorate vascular inflammation, vascular …

[HTML][HTML] Towards precritical medical therapy of the abdominal aortic aneurysm

L Musumeci, W Eilenberg, J Pincemail, K Yoshimura… - Biomedicines, 2022 - mdpi.com
… In animal models of AAA COX inhibitors are efficient in … -573 in mouse models of
atherosclerosis and various models of … To our knowledge there are no clinical trials using …

The macrophage polarization by miRNAs and its potential role in the treatment of tumor and inflammation

C Wang, X Wang, D Zhang, X Sun… - Oncology …, 2023 - spandidos-publications.com
inhibit the expression of some pro-inflammatory cytokines by targeting Semaphorin 3A and
STAT3 in macrophages of sepsis models (… The use of MDE as antagomir carriers can improve …

[HTML][HTML] Role of microRNAs in Immune Regulation with Translational and Clinical Applications

Z Gaál - International Journal of Molecular Sciences, 2024 - mdpi.com
… spontaneous multi-organ inflammation in a mouse model [23]. … in a murine model, miR-590-3p
mimics inhibited Th17 cells … Overexpression of miR-30a was found to ameliorate podocyte …

[HTML][HTML] Effects of cationic dendrimers and their complexes with microRNAs on immunocompetent cells

N Knauer, E Pashkina, A Aktanova, O Boeva… - Pharmaceutics, 2022 - mdpi.com
… As an oligonucleotide cargo, we use a synthetic mimic and an inhibitor of miR-155, an …
expression is highly specific for hematopoietic cells (in murine models) [23]. Expression of miR-…