… signaling is mediated by RelB/p52 heterodimerization and transactivation in response to
molecules such as B-… NF-κB targeting therapies inhibit signaling at specific points in canonical …

… NQO1 inhibition can reinforce survival signaling under … , increases in response to immunization
against prostate tumor … DIM in castrate-resistant, non-metastatic prostate cancer showed …

… after an initial response to AR inhibition, progression to the … progression of human
castrate-resistant prostate cancer. This … p65 in the restoration of sensitivity to AR inhibition in …

… Twist1 in response to AR inhibition, leading to CRPC (120). … , has been shown to restore
the sensitivity of tamoxifen to … upstream signaling activates the NF-κB pathway in response to …

… progression and the lack of response to current antiandrogen drugs. … Inhibition of NF-kB
signaling resensitizes castrate-resistant … RESTORE is a multicohort phase 2 study that includes …

… , further amplified the inhibition of androgen signaling. Celecoxib … Bioinformatic analyses on
human prostate cancer datasets … the EGFR-AR signaling in androgen-responsive PCa cells, …

… PCa, despite an initial response to ADT, subsequently induces … progression of PCa to
castrate-resistant and metastatic cancer. … that the inhibition of the NF-κB/Mcl-1 signaling pathway …

… /Akt pathway in response to enzalutamide and this activation leads to the inhibition of the pro…
In this sense, quercetin was able to restore sensitiveness to enzalutamide treatment in mice …

… finally develop into castrate-resistant prostate cancer (CRPC) … Downregulation of STAT3
gave rise to the restoration of the … in human CRPC via induction of ER stress response [21,49]. …

… The radiotherapy response is also … and restoring its expression is of importance in impairing
tumor progression in vitro and in vivo. miR-302b suppresses RELA NF-κB axis to inhibit EMT …