… to attenuate hypoxic pulmonary vasoconstriction in man. Other … nifedipine locally or reflexly
inhibits hypoxic pulmonary hyper… of nifedipine to reverse the pulmonary hypoxic response in …

… artery rings with endothelium whereas, and as expected, the contractile response was
markedly reduced by nifedipine and clevidipine. Hypoxic pulmonary vasoconstriction is a complex …

… and reversibly inhibited hypoxic pulmonary vasoconstriction. … inhibitor) and Notch (by 30
µM DAPT, a γ-secretase inhibitor) … study: (i) the blockers of VDCC, Nifedipine (Nif) (0.1 µM, for …

… we show that nifedipine treated hypoxic lung … nifedipine is known to reduce pulmonary
vasoconstriction in general [28], it is speculated that nifedipine may also inhibit hypoxic pulmonary …

… lung areas, preserving hypoxic pulmonary vasoconstriction (HPV), (4) exert effective
vasodilation … used drugs: PDE5 inhibitors, prostacyclin analogues and nifedipine, produced only …

… that nifedipine would not impair fetal sheep cardiac function under hypoxemic environment.
… Our findings suggest that in a hypoxemic environment nifedipine triggers detrimental effects …

… ROK also facilities vasoconstriction by reducing eNOS expression as the inhibition of ROK
increases eNOS expression in lungs of CH mice [… HPV Hypoxic pulmonary vasoconstriction …

… hypoxic pulmonary vasoconstriction but also redistribution of perfusion from obstructed lung
… Despite these promising results on NOS inhibition from preclinical models, clinical trials with …

… Inhibition of the RhoA/ROCK signaling pathway prevented the development of hypoxic
pulmonary … PA remodeling and pulmonary vasoconstriction. Immunoblotting results revealed that …

… organ systems, potently reduces hypoxic pulmonary vasoconstriction, improves minute
ventilation … decreased pulmonary pressure include Nifedipine and Phosphodiesterase inhibitors. …