[HTML][HTML] Local anaesthetics upregulate nitric oxide generation in cord blood and adult human neutrophils

KI Kulinska, M Billert, K Sawinski, K Czerniak… - Scientific Reports, 2019 - nature.com
… The reaction is catalyzed by nitric oxide synthase (NOS) 1 . In … inhibitors l-NAME and AG
partly and comparably reduced … activity of arginase I, needs to be taken into consideration 24 . …

Anesthesia‐Induced Oxidative Stress: Are There Differences between Intravenous and Inhaled Anesthetics?

T Senoner, C Velik-Salchner… - … medicine and cellular …, 2021 - Wiley Online Library
… as xanthine oxidase, nitric oxide synthase, cyclooxygenases, … of anesthesia with either
propofol or isoflurane increases both … The analgesic effects of N 2 O is caused by the inhibition of …

[HTML][HTML] Mechanisms of cancer inhibition by local anesthetics

Y Zhang, Y Jing, R Pan, K Ding, R Chen… - Frontiers in …, 2021 - frontiersin.org
reduces the dose of general anesthetics, improves the anesthetic effect and reduces the …
stronger evidence that LAs inhibit tumor progression, and relevant clinical guidelines will be …

[HTML][HTML] European Society of Anaesthesiology Task Force on Nitrous Oxide: a narrative review of its role in clinical practice

W Buhre, N Disma, J Hendrickx, S DeHert… - … journal of anaesthesia, 2019 - Elsevier
… gases among which were nitric oxide (NO), nitrous oxide (N 2 … the potent inhaled anaesthetic
can be reduced proportionally. … cobalt atom in cobalamin to inhibit the activity of the vitamin …

Role of endothelial nitric oxide synthase in isoflurane conditioning‐induced neurovascular protection in subarachnoid hemorrhage

U Athiraman, K Jayaraman, M Liu, T Giri… - Journal of the …, 2020 - Am Heart Assoc
… Isoflurane concentration in the anesthetic induction chamber … In the central nervous system,
inhalational anesthetics have … where we show isoflurane increases expression of eNOS in …

[HTML][HTML] The effects of volatile anesthetics on lung ischemia-reperfusion injury: basic to clinical studies

Y Oshima, A Otsuki, R Endo, M Nakasone… - Journal of Surgical …, 2021 - Elsevier
… a lower boiling point (22.8C) than other volatile anesthetics and … At anesthesia induction,
she was given an intravenous … are recruited, and platelets and nitric oxide synthase (NOS) are …

Effects of anesthetic agents and other drugs on cerebral blood flow, metabolism, and intracranial pressure

M Matsumoto, A Yamashita - Cottrell & Patel's Neuroanesthesia, 2025 - Elsevier
… that generate nitric oxide (NO) and arachidonic acid derivatives downstream … In general,
intravenous anesthetics decrease cerebral … Neither inhibition of NO synthase nor blockade of β-…

The effects of general anesthetics on synaptic transmission

X Hao, M Ou, D Zhang, W Zhao, Y Yang… - Current …, 2020 - ingentaconnect.com
anesthetic effects in the central nervous system (CNS) [29-31]. Volatile anesthetics decrease
… ), these intravenous general anesthetics were found to inhibit neurotransmitter release from …

[HTML][HTML] Mechanisms and efficacy of intravenous lipid emulsion treatment for systemic toxicity from local anesthetics

Y Liu, J Zhang, P Yu, J Niu, S Yu - Frontiers in Medicine, 2021 - frontiersin.org
… entry of the anesthetic into the blood vessel have been reduced. Clinical … nitric oxide
synthase, blocks the synthesis of nitric oxide, reduces the cerebral cortex spike reflex, and reduces

Inhibition of cAMP-phosphodiesterase 4 (PDE4) potentiates the anesthetic effects of Isoflurane in mice

IV Aragon, A Boyd, L Abou Saleh, J Rich… - Biochemical …, 2021 - Elsevier
… exploited to reduce the clinical doses of Isoflurane required to … of reagents (eg tail vein or
intracerebroventricular injections) … , inhalation anesthetics are widely used in children, and no