μ-Opioid receptors on distinct neuronal populations mediate different aspects of opioid reward-related behaviors
AL Severino, N Mittal, JK Hakimian, N Velarde… - eneuro, 2020 - eneuro.org
… cycle with ad libitum access to food and water, and experiments … MORs from D1
receptor-expressing neurons prevents opioid-… both A2a and μ opioid but not necessarily D2 …
receptor-expressing neurons prevents opioid-… both A2a and μ opioid but not necessarily D2 …
Effect of selective lesions of nucleus accumbens µ-opioid receptor-expressing cells on heroin self-administration in male and female rats: a study with novel Oprm1 …
JM Bossert, CA Mejias-Aponte, T Saunders… - Journal of …, 2023 - Soc Neuroscience
… -Cre rats and had a stronger inhibitory effect on the effort to self… addictive effects of opioid
drugs. However, in rat models of … and third base pair of the stop codon located in Oprm1 exon 4. …
drugs. However, in rat models of … and third base pair of the stop codon located in Oprm1 exon 4. …
[HTML][HTML] Distinct µ-opioid ensembles trigger positive and negative fentanyl reinforcement
F Chaudun, L Python, Y Liu, A Hiver, J Cand, BL Kieffer… - Nature, 2024 - nature.com
… Among the opioid receptors, µ-opioid receptors have a key … Here we injected mice with
fentanyl to acutely inhibit γ-… of the µ-opioid receptors (µORs) prevents the induction of …
fentanyl to acutely inhibit γ-… of the µ-opioid receptors (µORs) prevents the induction of …
Blocking μ-opioid receptors attenuates reinstatement of responding to an alcohol-predictive conditioned stimulus through actions in the ventral hippocampus
MR LeCocq, P Chander, N Chaudhri - Neuropsychopharmacology, 2023 - nature.com
… Importantly, we show that blocking MORs in the vHipp prevents … to δ-opioid receptors (DORs)
and κ-opioid receptors (KORs), … removing the inhibitory influence on GABA transmission. …
and κ-opioid receptors (KORs), … removing the inhibitory influence on GABA transmission. …
Central opioid receptors mediate morphine-induced itch and chronic itch via disinhibition
… interaction between µ-opioid receptor isoform 1D (MOR1D) … s to prevent thermal injury.
Tail-flick latency was determined … that intrathecal opioid acts upon MORs on spinal inhibitory …
Tail-flick latency was determined … that intrathecal opioid acts upon MORs on spinal inhibitory …
Dopamine and opioids inhibit synaptic outputs of the main island of the intercalated neurons of the amygdala
GC Gregoriou, SA Kissiwaa, SD Patel… - European Journal of …, 2019 - Wiley Online Library
… of dopamine D1-receptor and μ-opioid receptor, release … required for synaptic experiments
prevents description of the … from these inputs both inhibits GABAergic transmission (red) …
prevents description of the … from these inputs both inhibits GABAergic transmission (red) …
Nalmefene attenuates reinstatement of methamphetamine-seeking behavior in rats through group II metabotropic glutamate receptors (mGluR2/3)
Y Nawata, R Ooishi, T Nishioku… - Behavioural Brain …, 2024 - Elsevier
… that both μ opioid receptors (MORs) and κ opioid receptors (… DA and Glu transmission in
the ventral tegmental area and its … prevents the inhibitory effects of N-acetylcysteine on drug-…
the ventral tegmental area and its … prevents the inhibitory effects of N-acetylcysteine on drug-…
[HTML][HTML] Opioid-Induced Reductions in Amygdala Lateral Paracapsular GABA Neuron Circuit Activity
JW Ronström, NL Johnson, ST Jones… - International journal of …, 2023 - mdpi.com
… is regulated by two groups of inhibitory gamma aminobutyric … neurons highly express
inhibitory μ-opioid receptors (MORs) [16… The widefield epifluorescent and brightfield transmitted …
inhibitory μ-opioid receptors (MORs) [16… The widefield epifluorescent and brightfield transmitted …
Kappa opioid receptors drive a tonic aversive component of chronic pain
SS Liu, S Pickens, NE Burma… - Journal of …, 2019 - Soc Neuroscience
… effects in both male and female naive mice, but did not prevent … The rewarding effects of
intra-VTA injection of the μ-opioid … Because KOR inhibition by JDTic recovered morphine-evoked …
intra-VTA injection of the μ-opioid … Because KOR inhibition by JDTic recovered morphine-evoked …
[HTML][HTML] Frequency of the dopamine receptor D3 (rs6280) vs. opioid receptor µ1 (rs1799971) polymorphic risk alleles in patients with opioid use disorder: a …
MC Gondré-Lewis, I Elman, T Alim, E Chapman… - Biomedicines, 2022 - mdpi.com
… had no effect in opioid-naive rats, such blockade prevented the … the µ opioid receptor, which
is a potent mediator of the opioids’ … via two distinct opioid receptors: (a) inhibition via µ opioid …
is a potent mediator of the opioids’ … via two distinct opioid receptors: (a) inhibition via µ opioid …