[HTML][HTML] Mu-opioid receptor-expressing neurons in the paraventricular thalamus modulate chronic morphine-induced wake alterations
D Eacret, E Manduchi, J Noreck, E Tyner… - Translational …, 2023 - nature.com
… [17], and sucrose but not food seeking [18] all engage sleep-… 55], which may have prevented
any further increases in cFOS … The mu opioid receptor is an inhibitory, Gi-coupled receptor, …
any further increases in cFOS … The mu opioid receptor is an inhibitory, Gi-coupled receptor, …
Opioid Peptides and Their Receptors
R Przewlocki - Neuroscience in the 21st Century: From Basic to …, 2022 - Springer
… (SNPs) in the μ opioid receptor alone have been described in … The inhibition of opioid
receptors by opioid antagonists had … Blockade of opioid receptors with naloxone prevents the …
receptors by opioid antagonists had … Blockade of opioid receptors with naloxone prevents the …
Metabolic hormone action in the VTA: Reward-directed behavior and mechanistic insights
CE Geisler, MR Hayes - Physiology & behavior, 2023 - Elsevier
… Ghrelin also stimulates ĸ-opioid receptor inhibition of VTA … absence of food (4) but stimulates
µ-opioid receptor inhibition of … Inhibition NO or cGMP synthesis prevented systemic ghrelin …
µ-opioid receptor inhibition of … Inhibition NO or cGMP synthesis prevented systemic ghrelin …
Molecular mechanisms of morphine tolerance and dependence; novel insights and future perspectives
… The inhibition of the NOS and MnSOD activation has been shown to … other µ-opioid
receptor antagonist like naloxone in the treatment of opioid withdrawal. Clonidine, an α 2 -adrenergic …
receptor antagonist like naloxone in the treatment of opioid withdrawal. Clonidine, an α 2 -adrenergic …
Kappa opioid signaling at the crossroads of chronic pain and opioid addiction
… neurons normally act to prevent low-threshold mechanical … can either inhibit or facilitate
nociceptive transmission; … was recently rejected by the US Food and Drug Administration. …
nociceptive transmission; … was recently rejected by the US Food and Drug Administration. …
[HTML][HTML] A novel Oprm1-Cre mouse maintains endogenous expression, function and enables detailed molecular characterization of μ-opioid receptor cells
J Mengaziol, AD Dunn, G Salimando, L Wooldridge… - Plos one, 2022 - journals.plos.org
… of both the therapeutic and abused properties of opioids are … embryo) in order to inhibit NHEJ
and increase the frequency … was inserted upstream of the Oprm1 stop codon, in Exon 4. A …
and increase the frequency … was inserted upstream of the Oprm1 stop codon, in Exon 4. A …
Cocaine dysregulates dynorphin modulation of inhibitory neurotransmission in the ventral pallidum in a cell-type-specific manner
K Inbar, LA Levi, N Bernat, T Odesser… - Journal of …, 2020 - Soc Neuroscience
… , an opioid neuropeptide that binds δ- and μ-opioid receptors, inhibits … H–K, NorBNI did not
affect, and prevented the effects of … successfully suppressed GABA transmission from both D1-…
affect, and prevented the effects of … successfully suppressed GABA transmission from both D1-…
HSP90 inhibition in the mouse spinal cord enhances opioid signaling by suppressing an AMPK-mediated negative feedback loop
KA Gabriel, JM Streicher - Science signaling, 2023 - science.org
… Opioids and other agonists of the μ-opioid receptor are … We chose CGRP because it
contributes to pain transmission … that goes on to deactivate or prevent the activation of ERK. One …
contributes to pain transmission … that goes on to deactivate or prevent the activation of ERK. One …
[HTML][HTML] Crosstalk between opioid and anti-opioid systems: An overview and its possible therapeutic significance
E Gibula-Tarlowska, JH Kotlinska - Biomolecules, 2020 - mdpi.com
… into account their inhibitory influence on opioid-induced … are located in areas involved in the
following: (1) pain transmission… antagonists have been found useful in preventing relapse in …
following: (1) pain transmission… antagonists have been found useful in preventing relapse in …
The interaction between spinal pdgfrβ and μ opioid receptor in the activation of microglia in morphine-tolerant rats
Z Li, X Jia, X Peng, F Gao - Journal of Pain Research, 2020 - Taylor & Francis
… , more efficient therapeutic strategies to prevent, attenuate, or … were both inhibited by naloxone
( Figure 3B and C ). … in regulation of opioid tolerance within both spinal and supraspinal …
( Figure 3B and C ). … in regulation of opioid tolerance within both spinal and supraspinal …