… A series of synthesized phosphorylated flavonoids exhibited significantly improved inhibition
potency towards porcine … These phosphorylated flavonoids were irreversible competitive …

… The phosphorylated flavonoids were tested for the inhibition of carboxylesterases [32]. This
is a family of enzymes … Some of these phosphorylated flavonoids were identified as potent …

… phosphorylated flavonoids and identified 7-phosphorylated chrysin as the most effective
and selective inhibitor of … esterase (CEase) and porcine liver carboxylesterase (CE) with low …

… in discovery of hCES inhibitors from clinically available … Three comprehensive lists of hCES
inhibitors deriving from … , alongside with their inhibition potentials and inhibition parameters, …

… Compound 3 (IC50 㸺 50 ȣM) displayed the most potent inhibition … potent telomerase inhibitors
derived from flavonoids [23]. … develop more effective flavonoidtype hCE2 inhibitors [152]. …

… the phosphorylation of acetyl coenzyme A carboxylesterase (… These flavonoids significantly
inhibited the production of … closely related to the inhibition of phosphorylated forms of NF-κB …

… flavonoids with hydroxyl groups at the C3 and C6 and prenyl moieties at C8 site are able to
inhibit human carboxylesterase … a series of tyrosine phosphorylation events that leads to the …

… alternative splicing, posttranslational modification like phosphorylation, and epigenetic control
via … , the mode of inhibition was determined as competitive. Other major flavonoids such as …

… Gu Zhi include coumarins, flavonoids, meroterpenes, benzofuran… IBC bonded the active
pocket of carboxylesterase 1 (CES1), … of STAT6 phosphorylation and subsequent inhibition of the …

… in βoxidation and oxidative phosphorylation in mitochondria, … of the Nrf2/carboxylesterase 1
signaling pathway involved in the … This study suggests that flavonoid compounds can induce …