[HTML][HTML] Cardiovascular effects of caffeic acid and its derivatives: a comprehensive review

H Silva, NMF Lopes - Frontiers in physiology, 2020 - frontiersin.org
inhibition of potassium or PE-mediated constriction. In intact vessels this relaxation is not
inhibited by … Pyrrolidinyl caffeamide also induces phosphorylation of protein kinase B (AKT) and …

Fighting the flu: a brief review on anti-influenza agents

S Chakraborty, A Chauhan - Biotechnology and Genetic …, 2023 - Taylor & Francis
Flavonoid compounds are abundantly found in plants, and their primary purpose is to inhibit
NA and membrane fusion. According to a Structure-Activity Relationship (SAR) research, …

Evaluation of the efficacy of selected anticancer compounds in multidrug resistant cell culture models

MJ Rossouw - 2019 - repository.nwu.ac.za
… The 3-(4,5-dimethylthiazol-2-Yl)-2,5-diphenyltetrazolium bromide (MTT) assay was used as
a preliminary screening tool to determine the relative cell viability inhibitory concentration (IC…

[HTML][HTML] Insect cell-based models: cell line establishment and application in insecticide screening and toxicology research

X He, L Lu, P Huang, B Yu, L Peng, L Zou, Y Ren - Insects, 2023 - mdpi.com
… -coumaronochromone, together with eleven known flavonoids is detached from the ethanol
… complex 1 via inhibition of the downstream TSC1/TSC2 complex. Phosphorylation of TSC2 …

[HTML][HTML] Potential anti-SARS-CoV-2 therapeutics that target the post-entry stages of the viral life cycle: A comprehensive review

RA Al-Horani, S Kar - Viruses, 2020 - mdpi.com
… , the drug is to be activated by phosphorylation to generate the … by the action of human
carboxylesterase 1 (CES1) and/or … Other flavonoids have recently been reported as potential …

Mechanisms underlying dose-limiting toxicities of conventional chemotherapeutic agents

MA Manavi, MH Fathian Nasab… - Journal of …, 2023 - Taylor & Francis
… It’s worth noting that the addition of quercetin, a natural flavonoid … of caveolin-1, phosphorylation
and palmitoylation, may be … to SN38 in the liver by carboxylesterase enzyme, especially …

Physicochemical, permeability, antioxidant and anti-inflammatory properties of oxyresveratrol ester prodrugs

W Thaweesest - 2019 - digital.car.chula.ac.th
… The expression pattern of carboxylesterase (CES) in Caco-2 cell monolayer is completely
… to the human liver that expresses a much higher level of human carboxylesterase (hCES)-1 …

[图书][B] Pharmaceutical biocatalysis: chemoenzymatic synthesis of active pharmaceutical ingredients

P Grunwald - 2019 - books.google.com
… with the synthesis of inhibitors for isoprenoid biosynthesis. These inhibitors find application
as … acetate or pyruvate kinase for repeated phosphorylation of glycerol using glycerol kinase. …

Comprehensive review of cannabis including cannabinoid brain function

Y Shoyama - Medical Research Archives, 2023 - esmed.org
… such asterpenoids, flavonoids, and sterols were found6. … oxidative stress and tau
phosphorylation in AD patients without … ences from carboxylesterases of rabbit and porcine liver, …

Investigation of Pyrrolizidine Alkaloid-induced Liver Fibrosis and Therapeutic Intervention

X Chen - 2020 - search.proquest.com
… RTS-induced distortion of liver architecture and inhibited the fibrosis … , microsomal and
cytosolic carboxylesterases catalyzed the … And the most common flavonoids in Radix Scutellariae …