Peptide-based inhibitors of fimbrial biogenesis in Porphyromonas gingivalis

SR Alaei, JH Park, SG Walker… - Infection and …, 2019 - Am Soc Microbiol
… inhibits extracellular polymerization of the Fim fimbriae, … FimA subunit inhibited polymerization
of the Fim fimbriae on the … subunit-subunit interactions and fimbrial polymerization, which …

[PDF][PDF] The role of minor fimbriae in pathological interaction of Porphyromonas gingivalis with neutrophils: in vitro and in vivo studies

N Zubrzycka - 2024 - ruj.uj.edu.pl
Porphyromonas gingivalis is an anaerobic Gram-negative bacterium highly correlated with
chronic periodontitis and other oral conditions. P. … gingivalis and the role of the minor fimbriae

A Tale of Two Fimbriae: How Invasion of Dendritic Cells by Porphyromonas gingivalis Disrupts DC Maturation and Depolarizes the T-Cell-Mediated Immune …

MM Meghil, M Ghaly, CW Cutler - Pathogens, 2022 - mdpi.com
gingivalis fimbriae in the invasion of DCs, intracellular signaling, … play a crucial role in nearly
all interactions between the … gingivalis-loaded DCs through the inhibition of apoptosis and …

Porphyromonas gingivalis survival skills: Immune evasion

S Zheng, S Yu, X Fan, Y Zhang, Y Sun… - Journal of …, 2021 - Wiley Online Library
Porphyromonas gingivalis fimbriae and GECs surface receptors, … degrades organelles,
proteins, intracellular bacteria, and other … to inhibition of phagocytosis of infected apoptotic cells. …

Anti-biofilm activities of coumarin as quorum sensing inhibitor for Porphyromonas gingivalis

Z He, W Jiang, Y Jiang, J Dong, Z Song… - Journal of oral …, 2022 - Taylor & Francis
… of extracellular polysaccharides (EPS), proteins, lipids, and … coumarin exhibited a potent
inhibitory effect against QS systems, … gingivalis possesses two distinct types of fimbria, which are …

Adhesion and invasion of gingival epithelial cells by Porphyromonas gulae

H Inaba, R Nomura, Y Kato, H Takeuchi, A Amano… - PloS one, 2019 - journals.plos.org
… significantly inhibited adhesion and invasion by P. gulae. … The numbers of adherent and/or
intracellular bacteria were … gingivalis fimbriae mediate bacterial interactions for host tissue …

The sialidase inhibitor, DANA, reduces Porphyromonas gingivalis pathogenicity and exerts anti‐inflammatory effects: An in vitro and in vivo experiment

S Yu, X Fan, S Zheng, L Lin, J Liu… - Journal of …, 2021 - Wiley Online Library
… Untreated cells had intact cell membranes, clear intracellular … to further enhance the
interaction between the compound and the … gingivalis largely colonizes via FimA fimbriae, which …

Limonium brasiliense rhizomes extract against virulence factors of Porphyromonas gingivalis: Inhibition of gingipains, bacterial adhesion, and biofilm formation

R Isolani, F Pilatti, MN de Paula, L Valone, EL da Silva… - Fitoterapia, 2024 - Elsevier
fimbriae allowing recognition and adhesion to epithelial cells, fibroblasts, erythrocytes, and
certain components of the extracellular … to exclude potential cell growth inhibition effects [27]. …

Quercetin inhibits virulence properties of Porphyromas gingivalis in periodontal disease

Z He, X Zhang, Z Song, L Li, H Chang, S Li, W Zhou - Scientific reports, 2020 - nature.com
Porphyromonas gingivalis is a causative agent in the onset … gingipain proteases,
haemagglutinin, fimbriae, capsule, … in a self-produced extracellular polymeric substances matrix …

Local and Systemic Effects of Porphyromonas gingivalis Infection

WA Chen, Y Dou, HM Fletcher, DS Boskovic - Microorganisms, 2023 - mdpi.com
gingivalis mutants to extracellular matrix (ECM) protein … gingivalis fimbriae serve dual functions
during the pathogenesis … human gingival epithelial cells is inhibited in a double knockout …