Isolation, characterization, and fibroblast uptake of bacterial extracellular vesicles from Porphyromonas gingivalis strains

HR Haugsten, AK Kristoffersen, TM Haug… - …, 2023 - Wiley Online Library
… Adding the inhibitor KYT-1 showed inhibited gingipain activity both for strain ATCC 33277 …
gingivalis strains interact differently with fibroblasts due to fimbriae variations, the presence or …

[HTML][HTML] Pathogenesis of Important Virulence Factors of Porphyromonas gingivalis via Toll-Like Receptors

L Jia, N Han, J Du, L Guo, Z Luo, Y Liu - Frontiers in cellular and …, 2019 - frontiersin.org
inhibitor of TLR4. As the specific homolog of TLR4, CD180 is not the same Toll family receptor
as other TLRs due to the loss of an intracellularPorphyromonas gingivalis long fimbrial

The sialidase inhibitor, DANA, reduces Porphyromonas gingivalis pathogenicity and exerts anti‐inflammatory effects: An in vitro and in vivo experiment

S Yu, X Fan, S Zheng, L Lin, J Liu… - Journal of …, 2021 - Wiley Online Library
… Untreated cells had intact cell membranes, clear intracellular … to further enhance the
interaction between the compound and the … gingivalis largely colonizes via FimA fimbriae, which …

Host surface ectonucleotidase-CD73 and the opportunistic pathogen, Porphyromonas gingivalis, cross-modulation underlies a new homeostatic mechanism for …

JS Lee, N Chowdhury, JAS Roberts, Ö Yilmaz - Virulence, 2020 - Taylor & Francis
… role in the intracellular persistence of Porphyromonas gingivalis, a major … that IL-6 may exert
an inhibitory effect on intracellular P. … interactions can present a significant advantage for P. …

Quercetin inhibits virulence properties of Porphyromas gingivalis in periodontal disease

Z He, X Zhang, Z Song, L Li, H Chang, S Li, W Zhou - Scientific reports, 2020 - nature.com
Porphyromonas gingivalis is a causative agent in the onset … gingipain proteases,
haemagglutinin, fimbriae, capsule, … in a self-produced extracellular polymeric substances matrix …

[PDF][PDF] The virulence system of Porphyromonas gingivalis: Genes, mechanism and potential role of gingipains inhibitors.

…, S Fuloria, M Ravichandran, P Lalitha - Malaysian Journal of …, 2021 - researchgate.net
… of highly potent and safe gingipain inhibitor is a major concern for … Porphyromonas gingivalis
uses fimbriae to adhere and … cell response and the subsequent intracellular signaling in an …

PPAD activity promotes outer membrane vesicle biogenesis and surface translocation by Porphyromonas gingivalis

DM Vermilyea, MF Moradali, HM Kim… - Journal of …, 2021 - Am Soc Microbiol
… To test this hypothesis, surface translocation of fimbriated strain 381 and its … of intracellular
spermidine. Overall, the data support our model that PPAD impacts the transition between

[HTML][HTML] Rapid Release Polymeric Fibers for Inhibition of Porphyromonas gingivalis Adherence to Streptococcus gordonii

MY Mahmoud, S Sapare, KC Curry, DR Demuth… - Frontiers in …, 2020 - frontiersin.org
… gordonii, is mediated by the interaction of the minor fimbrial antigen, Mfa1, of P. gingivalis with
Extracellular LDH was quantified using a CytoTox96 ® non-radioactive cytotoxicity assay (…

Immunological Pathways Triggered by Porphyromonas gingivalis and Fusobacterium nucleatum: Therapeutic Possibilities?

KQ De Andrade, CLC Almeida-da-Silva… - Mediators of …, 2019 - Wiley Online Library
… receptor activation by extracellular ATP is necessary for IL-1β release after P. … gingivalis
fimbriae, because we showed that receptor expression had a … Inhibition of these pathways by P. …

[HTML][HTML] Porphyromonas gingivalis interaction with Candida albicans allows for aerobic escape, virulence and adherence

CA de Jongh, FJ Bikker, TJ de Vries, A Werner, S Gibbs… - Biofilm, 2024 - Elsevier
… its pathogenicity by degrading host extracellular matrix and adhesion … gingivalis ATCC
332777 has minor fimbriae, unlike P. … The current study adds on this by showing that inhibition of …