[HTML][HTML] Tissue-specific inflammation and insulin sensitivity in subjects with obesity

SM Oussaada, M Kilicarslan, BA de Weijer… - Diabetes Research and …, 2024 - Elsevier
… iii) had normal glucose tolerance during a standard 75-g oral … with basal or insulin-mediated
suppression of lipolysis after … Subcutaneous adipose tissue (SAT) and skeletal muscle (…

Differences in the link between insulin sensitivity and ectopic fat in men of Black African and White European ethnicity

O Bello, M Ladwa, O Hakim, C Marathe… - European journal of …, 2020 - academic.oup.com
glucose tolerance, we performed a two-step hyperinsulinaemic–… skeletal muscle, hepatic
and adipose tissue insulin sensitivity in … Insulin-mediated suppression of glycerol was used as a …

The phospholipase A2 family's role in metabolic diseases: Focus on skeletal muscle

I Prunonosa Cervera, BM Gabriel, P Aldiss… - Physiological …, 2021 - Wiley Online Library
… responsible for insulin-mediated glucose uptake, exhibits … a role in promoting fat accumulation
in adipose tissue and liver … for obesity and other obesity-related diseases such as fatty

[HTML][HTML] Insulin resistance and insulin sensitizing agents

L Mastrototaro, M Roden - Metabolism, 2021 - Elsevier
… between skeletal muscle, liver and adipose tissue during the … The infusion of IL-6 increases
insulin-mediated glucose … improve glucose tolerance and insulin sensitivity in obese mice […

Adipose tissue inflammation is directly linked to obesity-induced insulin resistance, while gut dysbiosis and mitochondrial dysfunction are not required

HL Petrick, KP Foley, S Zlitni, HS Brunetta… - Function, 2020 - academic.oup.com
… metabolic changes in skeletal muscle, adipose tissue, liver, the … and glucose intolerance
are closely linked with obesity in … adipose tissue impairs insulin-mediated suppression of …

[HTML][HTML] New insights into the role of insulin and hypothalamic-pituitary-adrenal (HPA) axis in the metabolic syndrome

JA Janssen - International journal of molecular sciences, 2022 - mdpi.com
fatty acid levels by increasing adipose tissue lipolysis [33]. … In the skeletal muscles, insulin
facilitates uptake of glucoseinsulin-mediated glucose uptake and disposal in muscles. …

Pioglitazone reduces epicardial fat and improves diastolic function in patients with type 2 diabetes

AJ Moody, M Molina‐Wilkins, GD Clarke… - Diabetes, Obesity …, 2023 - Wiley Online Library
… a measure of whole-body insulin-mediated glucose disposal. … epicardial adipose tissue
and paracardial adipose tissue … is a potent insulin sensitizer in skeletal muscle, liver, and …

[HTML][HTML] Effects of SGLT2 inhibition on lipid transport in adipose tissue in type 2 diabetes

KM Lauritsen, JH Voigt, SB Pedersen… - Endocrine …, 2022 - ec.bioscientifica.com
… Finally, a standard oral glucose tolerance test (OGTT) was … in skeletal muscle despite reducing
adipose tissue GLUT4 (28). … adipose tissue has a reduced insulin-mediated suppression

Lipid metabolism in sarcopenia

A Al Saedi, DA Debruin, A Hayes, M Hamrick - Bone, 2022 - Elsevier
… kinase activity, resulting in insulin-mediated alterations. … Remarkably, skeletal muscle from
type 2 diabetics had lower … to cross-talk between adipose tissue and skeletal muscle, as both …

Clinical features of nonobese, apparently healthy, Japanese men with reduced adipose tissue insulin sensitivity

D Sugimoto, Y Tamura, K Takeno… - The Journal of …, 2019 - academic.oup.com
… participant underwent an oral glucose tolerance test (OGTT) or … the degree of insulin-mediated
suppression of circulating FFAs (… the 50% suppression of lipolysis for 50% suppression of …