[图书][B] Proteomic and metabolomic approaches to biomarker discovery
HJ Issaq, TD Veenstra - 2019 - books.google.com
… Mass spectrometry-based strategies to improve biomarker … be shown to corre- late with the
characteristics of the disease.2 … are two well-known biomarkers for monitoring breast cancer. …
characteristics of the disease.2 … are two well-known biomarkers for monitoring breast cancer. …
Mass Spectrometry–Based Proteomics Analysis of Human Substantia Nigra From Parkinson's Disease Patients Identifies Multiple Pathways Potentially Involved in the …
… The subsequent protein–protein interaction analysis and the weighted gene coexpression
network analysis confirmed that the mitoribosome is the most enriched protein cluster. …
network analysis confirmed that the mitoribosome is the most enriched protein cluster. …
Bioinformatics methods for mass spectrometry-based proteomics data analysis
… [126] demonstrated better results can be achieved by … Their model also helped to identify
several potential biomarkers … functional differences between breast cancer subtypes. They …
several potential biomarkers … functional differences between breast cancer subtypes. They …
Identification of protein biomarkers for prediction of response to platinum‐based treatment regimens in patients with non‐small cell lung cancer
F Böttger, T Radonic, I Bahce, K Monkhorst… - Molecular …, 2023 - Wiley Online Library
… Using mass spectrometry-based proteomics, we have … For example, in our study of
BRCA1-deficient breast cancer [15], … We demonstrate the potential of proteomic analyses on …
BRCA1-deficient breast cancer [15], … We demonstrate the potential of proteomic analyses on …
Mass spectrometry‐based strategies for single‐cell metabolomics
… and facilitating novel biomarker discovery. With the … to analyze lipids in individual breast
cancer cells (SKBR-3). … This study demonstrated the capability to analyze cell extract …
cancer cells (SKBR-3). … This study demonstrated the capability to analyze cell extract …
An integrated mass spectrometry-based glycomics-driven glycoproteomics analytical platform to functionally characterize glycosylation inhibitors
… A glycosyltransferase used as a biomarker is UDP-N-acetyl-D-… acid ester, were previously
shown to inhibit the expression of … In breast cancer, the increased core fucosylation of EGFR …
shown to inhibit the expression of … In breast cancer, the increased core fucosylation of EGFR …
Quality will determine the future of mass spectrometry imaging in clinical laboratories: the need for standardization
… over conventional mass spectrometry-based techniques as it … ) sample (eg, breast cancer
tissue from a xenograft mouse … of the tumor biomarkers but also demonstrated the tissue …
tissue from a xenograft mouse … of the tumor biomarkers but also demonstrated the tissue …
Mass spectrometry and machine learning in the identification of COVID-19 biomarkers
LC Lazari, G Santos de Oliveira… - Frontiers in Analytical …, 2023 - frontiersin.org
… for COVID-19 biomarker discovery and validation. We also demonstrate that multiomics data
… This review will focus on mass spectrometry-based omics analyses; however, genomics …
… This review will focus on mass spectrometry-based omics analyses; however, genomics …
Mass spectrometry-based proteomics workflows in cancer research: the relevance of choosing the right steps
P Carrillo-Rodriguez, F Selheim… - Cancers, 2023 - mdpi.com
… Although Levin demonstrated that for a study to be powered … at the discovery of acute myeloid
leukemia (AML) biomarkers, … of breast cancer subtypes and for early detection of ovarian …
leukemia (AML) biomarkers, … of breast cancer subtypes and for early detection of ovarian …
Protein Biomarker Discovery: An Integrated Concept
AP Drabovich, E Martínez‐Morillo… - … Biological Discovery, 2019 - Wiley Online Library
… Proper validation includes measurement of each biomarker in … clinical samples are displayed,
including difficulty of sample … Mass spectrometry‐based assays may become an alternative …
including difficulty of sample … Mass spectrometry‐based assays may become an alternative …