Nucleoid-associated proteins (NAPs) such as IHF, HU, Fis, and H-NS alter the topology of
bound DNA and may thereby affect accessibility of DNA to repair and recombination
processes. To examine this possibility, we investigated the effect of IHF on the frequency of
homologous recombination (HR) and point mutations in soil bacterium Pseudomonas putida
by using plasmidial and chromosomal assays. We observed positive effect of IHF on the
frequency of HR, whereas this effect varied depending both on the chromosomal location of …