Opportunities involving microfluidics and 3D culture systems to the in vitro embryo production

MAMM Ferraz, GA Ferronato - Animal Reproduction, 2023 - SciELO Brasil
… Next, we explore the integration of 3D culture systems, including the use of biomimetic
scaffolds and organ-on-a-chip platforms, with a particular focus on the oviduct-on-a-chip. Finally, …

Understanding and assisting reproduction in wildlife species using microfluidics

S Le Gac, M Ferraz, B Venzac, P Comizzoli - Trends in biotechnology, 2021 - cell.com
Microfluidic devices present a high level of integration which comes in various flavors: (massive)
parallelization potential, the possibility to implement multi-step processes, and the …

Microfluidic systems for assisted reproductive technologies: Advantages and potential applications

RC Sequeira, T Criswell, A Atala, JJ Yoo - Tissue engineering and …, 2020 - Springer
… Furthermore, we discuss the possibility of future integration of these technologies onto a …
However, the distinct interspecies physiological differences between animals and humans, …

Advances of microfluidic technology in reproductive biology

A Nikshad, A Aghlmandi, R Safaralizadeh… - Life Sciences, 2021 - Elsevier
… this issue and have made therapeutic approaches by integrating biology, medicine, genetics,
… The most progressions have been seen in animal models. Results suggest that microfluidic

IVF-on-a-chip: recent advances in microfluidics technology for in vitro fertilization

L Weng - SLAS TECHNOLOGY: Translating Life Sciences …, 2019 - journals.sagepub.com
… IVF and Embryo Culture on a Chip An integrated microfluidic system has the prospect of
achieving IVF and embryo incubation with reduced human intervention, high efficiency, and …

Development of a microfluidic chip powered by EWOD for in vitro manipulation of bovine embryos

A Karcz, A Van Soom, K Smits, S Van Vlierberghe… - Biosensors, 2023 - mdpi.com
… In animal IVP, better results can be achieved when the in vivo matured ovum is used as …
compared to pipetting) as well as the possibility of sensor integration within the chip [51,52,53,54,…

Microfluidic multitissue platform for advanced embryotoxicity testing in vitro

JA Boos, PM Misun, A Michlmayr… - Advanced …, 2019 - Wiley Online Library
… on animals in vivo, about 90% of which are related to reproductive toxicology.4 According to
FDA standards, these animal … a microfluidic multitissue platform to seamlessly integrate liver …

Microfluidic Co‐Culture Platform to Recapitulate the Maternal–Placental–Embryonic Axis

JA Boos, PM Misun, G Brunoldi, LA Furer… - Advanced …, 2021 - Wiley Online Library
… toxicity studies rely on animal trials, while in vitro platforms that … in vitro model of 3D EBs,
we integrated a biological barrier model and expanded the experimental options of microfluidic

Microfluidic devices for gamete processing and analysis, fertilization and embryo culture and characterization

S Le Gac, V Nordhoff, B Venzac - … of Microfluidic Systems in Biology and …, 2019 - Springer
… different steps of the process, but also integrated and automated platforms. We will first present
… , although most of these platforms were tested on animal models. These platforms can be …

[HTML][HTML] Exploiting microfluidics for extracellular vesicle isolation and characterization: potential use for standardized embryo quality assessment

B Talebjedi, N Tasnim, M Hoorfar… - Frontiers in Veterinary …, 2021 - frontiersin.org
… of integrated microfluidic platforms for isolating and characterizing EVs from embryo culture
media, for embryo … The analysis of embryo-derived EVs in animals and humans is a relatively …