Stress and susceptibility: a systematic review of prenatal epigenetic risks for developing post-traumatic stress disorder

ZP Pierce, JM Black - Trauma, Violence, & Abuse, 2023 - journals.sagepub.com
… of prenatal susceptibility to post-traumatic stress disorder in the … -Met, a polymorphism of
FKBP5, and an altered messenger … related to post-traumatic stress disorder symptomatology. …

Hippocampal volume, FKBP5 genetic risk alleles, and childhood trauma interact to increase vulnerability to chronic multisite musculoskeletal pain

JJ Lobo, LJ Ayoub, M Moayedi, SD Linnstaedt - Scientific Reports, 2022 - nature.com
risk alleles in FKBP5 might interact to influence CMP vulnerability. In addition to brain anatomy
and FKBP5 … vulnerability factor for CMP is early life adversity via childhood trauma 35,36 . …

The role of childhood trauma, HPA axis reactivity and FKBP5 genotype on cognition in healthy individuals

A Ferrer, V Soria, N Salvat-Pujol, L Martorell… - …, 2021 - Elsevier
… associated with both childhood adversity and abnormalities of … We hypothesize that FKBP5
variations might interact with … personality disorder and post-traumatic stress disorder and …

Interaction Between Genes and Childhood Trauma on the Outcome of Psychiatric Disorders

M de Castro-Catala, S Papiol, N Barrantes-Vidal… - Childhood Trauma in …, 2020 - Springer
… In this case, although we will focus on childhood adversity, which … childhood trauma was
also observed in post-traumatic stress … The FKBP5childhood trauma interaction has also been …

Effect of interaction between a specific subtype of child abuse and the FKBP5 rs1360780 SNP on DNA methylation among patients with bipolar disorder

T Saito, G Shinozaki, M Koga, M Tanichi… - … of affective disorders, 2020 - Elsevier
… in mood disorder. Therefore, the purpose of this study was to investigate which subtypes of
child abuse are associated with the DNAm level of FKBP5 intron 7 through an interaction with …

The FKBP5 genotype and childhood trauma effects on FKBP5 DNA methylation in patients with psychosis, their unaffected siblings, and healthy controls

M Mihaljevic, D Franic, I Soldatovic, I Lukic… - …, 2021 - Elsevier
… questionnaire that measures five types of childhood adversities: emotional abuse, physical
… Furthermore, we observed a difference in FKBP5 methylation levels in the interaction of low …

Influence of FKBP5 Variants and Childhood Trauma on Brain Volume in Non-clinical Individuals

A Kwon, S Kim, H Jeon, HS Lee… - Frontiers in behavioral …, 2021 - frontiersin.org
… Furthermore, studies have identified the effects of childhood adversity on neural correlates of
… present study explored multiple FKBP5 SNPs and their interaction with the environment on …

The psychopathological potential of early life stress

JK Rybakowski - The World Journal of Biological Psychiatry, 2020 - Taylor & Francis
… role of stress in early life, named also ‘early life adversity’ or ‘… disorders such as major
depression and post-traumatic … the role of the FKBP5 gene in the sequels of childhood abuse is …

Working memory reflects vulnerability to early life adversity as a risk factor for substance use disorder in the FKBP5 cortisol cochaperone polymorphism, rs9296158

WR Lovallo, A Acheson, AJ Cohoon, KH Sorocco… - PLoS one, 2019 - journals.plos.org
… treatment have increased symptoms of post-traumatic stress disorder [18] and proneness to
… at risk for substance use disorders. Our published finding of a G x E interaction showed that …

Interaction of childhood trauma with BDNF and FKBP5 gene polymorphisms in predicting burnout in general occupational groups

Y Li, H Jia, X Wei, S Zhen, SC He, XY Zhang - European Archives of …, 2024 - Springer
… Therefore, we investigated the interaction of these two SNPs with childhood trauma in …
under high childhood trauma, thereby increasing their risk of post-traumatic stress disorder (PTSD) …