(8-Hydroxyquinoline) Gallium (III) Complex with High Antineoplastic Efficacy for Treating Colon Cancer via Multiple Mechanisms
SH Zhou, WH Liao, Y Yang, W Li, Y Wu, TT Wu… - ACS …, 2023 - ACS Publications
… provide a foundation for the development of gallium complexes as potent anticancer agents.
… explains the charge transfer interaction within the molecule. A higher value indicates that a …
… explains the charge transfer interaction within the molecule. A higher value indicates that a …
Solution speciation and human serum protein binding of indium (III) complexes of 8-hydroxyquinoline, deferiprone and maltol
… tris(maltolato)Ga(III) (GaM 3 ) are orally active antitumor metallodrugs recently undergone
… of the analogous Ga(III) complexes. Interaction of the tris-ligand complexes with LMM serum …
… of the analogous Ga(III) complexes. Interaction of the tris-ligand complexes with LMM serum …
8-Hydroxyquinoline-amino acid hybrids and their half-sandwich Rh and Ru complexes: Synthesis, anticancer activities, solution chemistry and interaction with …
… One of the most prominent compounds is the Ga(III) complex of HQ (tris(8-quinolinolato)gallium,
KP46), which had successfully entered clinical trials and it was effective against renal …
KP46), which had successfully entered clinical trials and it was effective against renal …
Competition between abiogenic and biogenic metal cations in biological systems: Mechanisms of gallium's anticancer and antibacterial effect
N Kircheva, T Dudev - Journal of Inorganic Biochemistry, 2021 - Elsevier
… mechanisms of gallium's therapeutic action in anticancer and … for Ga 3+ beneficial effect
such as the electrostatic interactions … with three maltol [tris(3- hydroxy-2methyl-pirone)] ligands) …
such as the electrostatic interactions … with three maltol [tris(3- hydroxy-2methyl-pirone)] ligands) …
Metal complexes of a 5-nitro-8-hydroxyquinoline-proline hybrid with enhanced water solubility targeting multidrug resistant cancer cells
T Pivarcsik, V Pósa, H Kovács, NV May… - International Journal of …, 2022 - mdpi.com
… so far, countless anticancer complexes of transition metal … Quantitative-NMR (via the use of
maltol as internal standard, … the interaction of this novel compound with Fe(III) and Fe(II) ions …
maltol as internal standard, … the interaction of this novel compound with Fe(III) and Fe(II) ions …
[PDF][PDF] Interaction between platinum group metal ions and novel ambidentate (N, N) and (O, O) chelating ligands in aqueous solution
S NAGY, A OZSVÁTH, AC BÉNYEI, E FARKAS… - … of Metal Complexes, 2021 - iris.unito.it
… Co (III), a second metal ion with proven anticancer potential (… derivatives of maltol
utilizing well-known literature methods [3]. … study of the coordination properties of 8-hydroxyquinoline-2-…
utilizing well-known literature methods [3]. … study of the coordination properties of 8-hydroxyquinoline-2-…
Alkyl gallium (III) quinolinolates: A new class of highly selective anti-leishmanial agents
… as the N,O donor 8-quinolinol (8-hydroxyquinoline, 8QH). The … phase II gallium anti-cancer
agents such as gallium maltolate… for the Ga–O bond is representative of a covalent interaction …
agents such as gallium maltolate… for the Ga–O bond is representative of a covalent interaction …
First Gallium and Indium Crystal Structures of Curcuminoid Homoleptic Complexes: All-Different Ligand Stereochemistry and Cytotoxic Potential
W Meza-Morales, Y Alvarez-Ricardo… - International Journal of …, 2023 - mdpi.com
… metal complexes of a curcuminoid, namely Dimethoxycurcumin (DiMeOC), with gallium
and indium. Such successful achievement can be attributed to the suppression of interactions …
and indium. Such successful achievement can be attributed to the suppression of interactions …
Speciation of metal complexes of medicinal interest: relationship between solution equilibria and pharmaceutical properties
T Kiss, ÉA Enyedy, T Jakusch… - Current Medicinal …, 2019 - ingentaconnect.com
… stream interacting with the serum/plasma components, (iii) … complexes and anticancer Ga(III)
complexes). Although Ru(… of the tris-ligand Ga complexes of maltol and 8quinolinol were …
complexes). Although Ru(… of the tris-ligand Ga complexes of maltol and 8quinolinol were …
New era in the treatment of iron deficiency anaemia using trimaltol iron and other lipophilic iron chelator complexes: historical perspectives of discovery and future …
GJ Kontoghiorghes, A Kolnagou, T Demetriou… - International Journal of …, 2021 - mdpi.com
… by lipophilic iron complexes of 8-hydroxyquinoline, tropolone… , the interaction of maltol and
the maltol iron complex with the … basic anticancer and antimicrobial targeting of maltol gallium …
the maltol iron complex with the … basic anticancer and antimicrobial targeting of maltol gallium …