… difference may provide a clinical advantage of IFN-α for the treatment of chronic HCV infection,
since type III IFNs cause less adverse hematopoietic effects than IFN-α. 55 Oh MD, Park …

… infected cells and innate immune cells. Dysregulation of host … been reported to interfere
with IFN responses are indicated. … prevent COVID-19 incidence without adverse effects, as the …

… During chronic infection and cancer, a new homeostasis is reached such that the negative
effects of IFN-Is … IFN-Is interfere with angiogenesis in three ways: They act directly on vascular …

… type III IFNs serve as a front-line defense that controls infection at epithelial barriers while
minimizing damaging … the more potent type I IFN response for when local responses are …

… ISGs), which have the capacity to interfere with every step of viral replication ( … IFN-mediated
antiviral response in coronavirus infection, focusing on the innate recognition of and immune …

… Next, we explore some of the ways viruses can interfere with, … wild-type IFN, which may
suggest that type I IFNs already exert … The organelle-damaging effects of certain viral infections …

… , type I and III IFNs play crucial roles in innate immune … the 5′-polyuridine sequences from
negative-sense viral RNA, inhibiting … ORF6 of SARS-CoV-2 also interferes with the nuclear …

… pathogen infections by controlling inflammation and immune … type II IFN is specific for
immune cells, type I and III IFNs are … of IFN signaling, numerous negative regulators interfering …

… that IFN-Is also played a negative role in antitumor immunity. … [ 55 ] These studies suggest
that IFN-α interferes simultaneously … During chronic viral infection, persistent IFN-I signaling …

… antiviral immunity. In this work, we show that IFN signaling interferes with lung repair during
… localized antiviral protection at the site of infection without driving damaging proinflammatory …