[HTML][HTML] A novel in vitro model to study prolonged Pseudomonas aeruginosa infection in the cystic fibrosis bronchial epithelium

MJ Hirsch, EM Hughes, MM Easter, SE Bollenbecker… - Plos one, 2023 - journals.plos.org
… C shows significant downregulation of interleukin 8. Our data … to chloride ion dysregulation
and thick mucus in epithelial tissue, … PA is a Gram-negative opportunistic pathogen that is well-…

[HTML][HTML] Biomarkers in urinary tract infections–which ones are suitable for diagnostics and follow-up?

J Horváth, B Wullt, KG Naber, B Köves - GMS infectious diseases, 2020 - ncbi.nlm.nih.gov
… lower UTIs react with local mucosal responses; febrile UTIs (f-… the siderophores on the
Gram-negative bacterial wall [12]. … along with serum CRP and neutrophil-lymphocyte ratio (NLR) …

[HTML][HTML] The Role of Helicobacter pylori Neutrophil-Activating Protein in the Pathogenesis of H. pylori and Beyond: From a Virulence Factor to Therapeutic Targets …

HW Fu, YC Lai - International Journal of Molecular Sciences, 2022 - mdpi.com
… , Gram-negative bacterium first … infected mice with this vaccine resolved gastritis but
failed to fully eliminate the colonized bacteria, despite the induction of mucosal IgA responses

[HTML][HTML] Blood gene expression biomarkers of response to anti-TNF drugs in pediatric inflammatory bowel diseases before initiation of treatment

S Salvador-Martín, G Rubbini, P Vellosillo… - Biomedicine & …, 2024 - Elsevier
… Functional enrichment analyses highlighted defense response to Gram-negative bacteria
(… who responded to anti-TNF therapy. The expression of CD66b in neutrophils from mucosa, …

[HTML][HTML] Molecular determinants of disease severity in urinary tract infection

I Ambite, D Butler, MLY Wan, T Rosenblad… - Nature Reviews …, 2021 - nature.com
… Fourth, the mucosal TLR4 response is attenuated in the … host response to Gram-negative
bacterial infection generally, … -8, IL-6 and neutrophil responses in patients inoculated with E. coli …

[HTML][HTML] Pathogenic mechanisms of Fusobacterium nucleatum on oral epithelial cells

S Groeger, Y Zhou, S Ruf, J Meyle - Frontiers in Oral Health, 2022 - frontiersin.org
mucosa, the lining mucosa, and the specialized mucosa, … sensing components of Gram-negative
bacteria, while NOD2 … et al. demonstrated that hBD2 and Interleukin-8 (IL)-8 could …

An Oral Inoculation Infant Rabbit Model for Shigella Infection

CJ Kuehl, JD D'Gama, AR Warr, MK Waldor - MBio, 2020 - Am Soc Microbiol
… Expression of the proinflammatory chemokine interleukin 8 (… Shigella species are Gram-negative,
rod-shaped bacteria that … response with mucosal ulceration and erosions, neutrophil

Pelvic Inflammatory Disease Due to Neisseria gonorrhoeae and Chlamydia trachomatis: Immune Evasion Mechanisms and Pathogenic Disease Pathways

T Darville - The Journal of infectious diseases, 2021 - academic.oup.com
… trachomatis are gram-negative pathogens that survive extra- … that elicit a robust mucosal
Th1 response that can cooperate … with primary infection, although neutrophils were reduced. …

[HTML][HTML] α-Lipoic Acid Inhibits IL-8 Expression by Activating Nrf2 Signaling in Helicobacter pylori-infected Gastric Epithelial Cells

S Kyung, JW Lim, H Kim - Nutrients, 2019 - mdpi.com
… in the α-LA-induced suppression of interleukin 8 (IL-8) and ROS. … pylori is a Gram-negative
bacterium, usually acquired during … human gastric mucosa by infiltration of neutrophils into the …

Novel assay to characterize neutrophil responses to oral biofilms

M Oveisi, H Shifman, N Fine, C Sun… - Infection and …, 2019 - Am Soc Microbiol
… oralis can generate the cytokine interleukin 8 (IL-8), activating additional neutrophils (58)
to … the neutrophils have a response to a healthy plaque in which the number of Gram-negative