… the role of INSTNs in viral endocytosis by interaction with signalling pathways. INSTN-2 …
enhancing ubiquitylation of EGFR by ubiquitin E3 ligase Cbl due to growth factor stimulation [25]. …

… This effect may involve regulation of RTK ubiquitylation and endocytosis by Cbl … (epidermal
growth factor receptor kinase substrate 8) interaction with Cbl leading to Eps8 ubiquitylation …

… the receptor, a signal that targets EGFR to degradation in lysosomes (4–6). Interestingly, CME
is also regulated by ubiquitination of endocytic … sprouty 2, intersectin disrupts the sprouty 2-…

… Thus, this ubiquitination would 235 need to be specific to … -bound protein 2, ITSN1 383
intersectin 1, NUMB protein numb … analysis of the epidermal growth factor receptor 434 (EGFR) …

… Epidermal growth factor receptor (EGFR) is a critical regulator … step for endocytosis as
mutations of EGFR ubiquitination sites … Intersectin is one of the possible candidates. As a scaffold-…

… structures where it governs cell signaling, differentiation and … To probe for this, we analyzed
EGF receptor endocytosis by … /ml TRITC-conjugated epidermal growth factor (EGF, Thermo …

… , intersectin promotes ubiquitination, endocytosis and degradation of epidermal growth
factor receptor (EGFR) and thereby terminates EGF signaling (Martin et al., 2006). Moreover, …

… How CCPs and clathrin may directly control EGFR signaling at the plasma membrane prior
to receptor endocytosis had remained … Epidermal growth factor receptor substrate 15 FAK …

… upon endocytosis as being an active and highly regulated process … required for IFNAR1
ubiquitination-dependent endocytosis. It is … growth factor receptor (FGFR) endosomal sorting and …

… , the CME of the EGFR is also regulated by ubiquitination of … (Vps4) promotes Epidermal
growth factor receptor signaling … where trafficking, polarity and signaling intersect. Along this line…