Interplay between diet, the gut microbiome, and atherosclerosis: Role of dysbiosis and microbial metabolites on inflammation and disordered lipid metabolism

L Anto, CN Blesso - The Journal of Nutritional Biochemistry, 2022 - Elsevier
… /L-carnitine diets may contribute to gut microbiome-dependent production of trimethylamine
N-oxide, contributing to atherosclerosis … diets can increase the gut microbiome production of …

The microbial gbu gene cluster links cardiovascular disease risk associated with red meat consumption to microbiota l-carnitine catabolism

JA Buffa, KA Romano, MF Copeland, DB Cody… - Nature …, 2022 - nature.com
… of l-carnitine, a nutrient abundant in red meat, are associated with CVD risks in subjects and
dietary l-carnitine enhances atherosclerosis in … Suppression of gut microbiota with poorly …

[HTML][HTML] l-Carnitine in omnivorous diets induces an atherogenic gut microbial pathway in humans

RA Koeth, BR Lam-Galvez, J Kirsop… - The Journal of …, 2019 - Am Soc Clin Investig
l-Carnitine, an abundant nutrient in red meat, accelerates atherosclerosis in mice via gut
microbiota… γBB is a major gut microbiota metabolite of l-carnitine, and TMA formation from γBB is …

… of foods containing L-carnitine and phosphatidylcholine on the production of the proatherogenic metabolite trimethylamine N-oxide and the intestinal microbiome in …

IV Trofimovich, KE Andreevna - 2019 - cabidigitallibrary.org
… The aim of the study was to assess the impact of L-carnitine and … in red meat, promotes
atherosclerosis // Nat. Med. 2013. … The gut microbiome in atherosclerotic cardiovascular disease. …

Gut microbiota in atherosclerosis: focus on trimethylamine N‐oxide

Y Zhu, Q Li, H Jiang - Apmis, 2020 - Wiley Online Library
L-carnitine are two principle nutrients precursors of TMAO, which are metabolized to TMA
by gut microbiota … is another dietary precursor of TMAO fond predominantly in red meat and …

[HTML][HTML] Gut Microbiome, Functional Food, Atherosclerosis, and Vascular Calcifications—Is There a Missing Link?

D Cretoiu, RF Ionescu, RM Enache, SM Cretoiu… - Microorganisms, 2021 - mdpi.com
intestinal microbiota and atherosclerosisL-carnitine from red meat and phosphatidylcholine
from egg yolks can also play a key role in the prevention of CVDs, including atherosclerosis (…

[HTML][HTML] Gut microbiota and its metabolites in atherosclerosis development

MD Pieczynska, Y Yang, S Petrykowski… - Molecules, 2020 - mdpi.com
… the Cleveland Clinic reported that lecithin and L-carnitine (present in red meat, egg yolk, etc.…
of intestinal microorganisms, which in turn promote the development of atherosclerosis and …

Dietary metabolism, the gut microbiome, and heart failure

WHW Tang, DY Li, SL Hazen - Nature Reviews Cardiology, 2019 - nature.com
… In the setting of cardiovascular disease, both atherosclerosis and increased platelet … , and
l-carnitine can be metabolized by particular species of the gut microbiota to trimethylamine (…

Dietary meat, trimethylamine N-oxide-related metabolites, and incident cardiovascular disease among older adults: the cardiovascular health study

M Wang, Z Wang, Y Lee, HTM Lai… - Arteriosclerosis …, 2022 - Am Heart Assoc
… that processed meat and unprocessed red meat consumption … gut microbiota-dependent
metabolites derived from dietary … suggest that L-carnitine derived microbiome metabolites play …

High l-Carnitine Ingestion Impairs Liver Function by Disordering Gut Bacteria Composition in Mice

Q Wu, X Zhang, Y Zhao, X Yang - Journal of agricultural and food …, 2020 - ACS Publications
… of high l-carnitine consumption on intestinal microbiota, liver function, and metabolite distribution
in … in animal sources such as red meat, and thus the acceptable daily intake (ADI) of red